ID D2SAC2_GEOOG Unreviewed; 579 AA.
AC D2SAC2;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin {ECO:0000313|EMBL:ADB75937.1};
GN OrderedLocusNames=Gobs_3335 {ECO:0000313|EMBL:ADB75937.1};
OS Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / KCC
OS A-0152 / KCTC 9177 / NBRC 13315 / NRRL B-3577 / G-20).
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Geodermatophilus.
OX NCBI_TaxID=526225 {ECO:0000313|EMBL:ADB75937.1, ECO:0000313|Proteomes:UP000001382};
RN [1] {ECO:0000313|EMBL:ADB75937.1, ECO:0000313|Proteomes:UP000001382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25078 / DSM 43160 / JCM 3152 / KCC A-0152 / KCTC 9177 /
RC NBRC 13315 / NRRL B-3577 / G-20 {ECO:0000313|Proteomes:UP000001382};
RX PubMed=21304698;
RA Ivanova N., Sikorski J., Jando M., Munk C., Lapidus A., Glavina Del Rio T.,
RA Copeland A., Tice H., Cheng J.-F., Lucas S., Chen F., Nolan M., Bruce D.,
RA Goodwin L., Pitluck S., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.-J., Jeffries C.D., Meincke L.,
RA Brettin T., Detter J.C., Detter J.C., Rohde M., Goeker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P.;
RT "Complete genome sequence of Geodermatophilus obscurus type strain (G-
RT 20).";
RL Stand. Genomic Sci. 2:158-167(2010).
RN [2] {ECO:0000313|Proteomes:UP000001382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25078 / DSM 43160 / JCM 3152 / KCC A-0152 / KCTC 9177 /
RC NBRC 13315 / NRRL B-3577 / G-20 {ECO:0000313|Proteomes:UP000001382};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Munk A.C., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Jando M.,
RA Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Geodermatophilus obscurus DSM 43160.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
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DR EMBL; CP001867; ADB75937.1; -; Genomic_DNA.
DR RefSeq; WP_012949367.1; NC_013757.1.
DR AlphaFoldDB; D2SAC2; -.
DR STRING; 526225.Gobs_3335; -.
DR KEGG; gob:Gobs_3335; -.
DR eggNOG; COG0791; Bacteria.
DR eggNOG; COG1876; Bacteria.
DR HOGENOM; CLU_031958_0_0_11; -.
DR OrthoDB; 1099523at2; -.
DR Proteomes; UP000001382; Chromosome.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd14814; Peptidase_M15; 1.
DR Gene3D; 3.30.1380.10; -; 1.
DR Gene3D; 6.10.250.3150; -; 1.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR009045; Hedgehog_sig/DD-Pept_Zn-bd_sf.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR003709; Pept_M15B.
DR PANTHER; PTHR34385; D-ALANYL-D-ALANINE CARBOXYPEPTIDASE; 1.
DR PANTHER; PTHR34385:SF1; PEPTIDOGLYCAN L-ALANYL-D-GLUTAMATE ENDOPEPTIDASE CWLK; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF02557; VanY; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF55166; Hedgehog/DD-peptidase; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:ADB75937.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:ADB75937.1};
KW Protease {ECO:0000313|EMBL:ADB75937.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001382};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..579
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003035789"
FT DOMAIN 293..417
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
FT COILED 54..109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 157..184
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 579 AA; 58396 MW; 5096EEAEC6F1000E CRC64;
MHSLSRWRPG RRAVASLSVG VVALAAVLSS ATPAGAAPAG AAVADASLLD SPELDALQRR
AAEVQADLQE RQSRVVAARE ALAAAEAAAA QAEADIVAAD AELARARAEV ARHASAVYRD
AGEVTPLSVL LSGGGPGDVV AAGGLLDAAE RHAAAVVAAA ERRRQEAAAR RAEAERTRET
ARARAAELTT GTAELEAAAA AASRDLEVAV AAVDRQLGRQ REEQRAAGRQ AATDWHGYLD
ELAAAGVTPP PAAALRDPVV GLPDGLAPVP ASGGGVQAGV AQLPGADPLV VPAAEAVAAV
SAAVDALELP YAPGAAGPDA WSCGSLVHAV YASVGIDLPD DQAGLYAGTT PVDPADVLPG
DLVFLGAGRS GPGNVGIALD RRTVLAADAR AGAVVVGRPA ADRVLGAGRP GLGPRAAVPA
TGPSGGALPV ECGDVRYPPE TSGGRAWRGF PNGLVPPGAM CPLGVAGHLL RCDAATAYQA
MSTAFAGAFG TPLCLTDSYR TYGEQVRLYG EKPELAAVPG TSDHGWGLAV DLCGGVEQFG
TAQYAWMVAN AGRFGFLHPR WADPGNGREE PWHWEYAGA
//
