ID   D2V6T2_NAEGR            Unreviewed;       769 AA.
AC   D2V6T2;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=DUF4116 domain-containing protein {ECO:0000259|Pfam:PF13475};
GN   ORFNames=NAEGRDRAFT_78818 {ECO:0000313|EMBL:EFC47497.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC   Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC47497.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC47497.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA   Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA   Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA   Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
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DR   EMBL; GG738854; EFC47497.1; -; Genomic_DNA.
DR   RefSeq; XP_002680241.1; XM_002680195.1.
DR   AlphaFoldDB; D2V6T2; -.
DR   EnsemblProtists; EFC47497; EFC47497; NAEGRDRAFT_78818.
DR   GeneID; 8849125; -.
DR   VEuPathDB; AmoebaDB:NAEGRDRAFT_78818; -.
DR   InParanoid; D2V6T2; -.
DR   OrthoDB; 5565395at2759; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   InterPro; IPR025197; DUF4116.
DR   Pfam; PF13475; DUF4116; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   DOMAIN          217..263
FT                   /note="DUF4116"
FT                   /evidence="ECO:0000259|Pfam:PF13475"
SQ   SEQUENCE   769 AA;  91966 MW;  8194C3BB522D42DC CRC64;
     MFSRDCPQNK QHNSSEEILL QQAQDDDEDL MINFCDFEFN LNLQSQIQDL AQIREFAKTI
     SYYKHHDNNR NSYDLCNDDW FMILDFIPFF EFSKFALVCS SFAELLTFNR RYLVMRRILK
     GFPILLKDHH YLPVESLEIL ANNEAPSDDP SFAKSIYSDM INFLFEKRRY KKNMWKNIPS
     TKILEMDQQV FILPFRDSMI RKVFSDFIDI PQVLLDDRDF ILKFFKSFPK APRYFTFLNS
     KLMQDEEIAK MAVQSNGWFI RFVQDPTSEI LNTAFCSRKR YIISSTSHHT FERYKESLIE
     FVREPFYHLL EQKSIVNDYR MSRKELFFKR NMIFDSKCGS KNAEFLLLFS FFEKSPEFKG
     VLLYFYNAKT STEKYDHIDD LITDLLCVPE KFQPILSKPM LVPEELKCKT REITMSTMLK
     NILDDNFTFD NVMTHDKKKL TTSSIEYLRE RLIQKMKPTP LFTGMYFGKK VENIDCENES
     EKIKLLNEIS KCRGLNMKML KYYPKHYVLL DEEIKQDEEF KRIAMRCLKF NAQYFDFSKD
     DMLVLLLSAN VKVSVEYLKK QSNWSSTLER INNIFTTNGR IRSNWLTWPQ VYCLYRFLLC
     YSFNRDKLFT LEDQVKMIDY IPPKHKKLLL EYSYEECLME KIRLKNLVQF DFYDSRVFLF
     GFRYMISYKS INAICRVVDG SLIKFQQSDR LLSEILKVTP KFIKVFMEKR PKIYRKVILP
     PYPVELVIKL ALENPRIIHY LPRNIQSHPL LLCGLMGIYR GQHNSTTGM
//