ID D2V7I0_NAEGR Unreviewed; 698 AA.
AC D2V7I0;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC47382.1};
GN ORFNames=NAEGRDRAFT_64809 {ECO:0000313|EMBL:EFC47382.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC47382.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC47382.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG738855; EFC47382.1; -; Genomic_DNA.
DR RefSeq; XP_002680126.1; XM_002680080.1.
DR AlphaFoldDB; D2V7I0; -.
DR STRING; 5762.D2V7I0; -.
DR EnsemblProtists; EFC47382; EFC47382; NAEGRDRAFT_64809.
DR GeneID; 8860372; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_64809; -.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR InParanoid; D2V7I0; -.
DR OMA; TPTAYVW; -.
DR OrthoDB; 362380at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR NCBIfam; TIGR00728; OPT_sfam; 1.
DR PANTHER; PTHR31645; OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED; 1.
DR PANTHER; PTHR31645:SF0; OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED; 1.
DR Pfam; PF03169; OPT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 591..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 626..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 38..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 75626 MW; 825249DD735B3A21 CRC64;
MSEDARVDSA FHQEGNGGEV IKPQTTSNNK LGYVLMDDDE TTANDDDSLL KNGGDPFEEH
ERMDDENEAG LDTLRKRVAT QDVDDDDEEE FDENDTTEIG RFKERGEFTF RSIIVGALIG
ILVGAMNVNF GLRTGWTQGG SIFASILSIG VFKLIKPSRP FTKYETIITT TAASSAGTMA
STAGLVSSIP ALKLNGTNYN VGELYLWALS VAFFGVYFAV PLRKHLIVTE KLRFPTGTAT
AATIKSMFAQ GYETVKKARM LVFWGLFSAF YSLLIFLVPP IAEPPMPRVL HEFGFSLYLD
PLMIGGGMLS GPRSTGSLLL GAIVGWGVLA PIVDAYGWTK GAPMSFSGAR GWVLWVGVSI
MTADSFVQLL FLTKIIWQGL VGLVKRVAIR GSGRSTQRHF GERVILEHEQ YELDSHLIPW
WYCLIGICIS SVLLILIGHF MFELKWYFIL LAIPLSGVLS IVATRATGET DINPVGGMGK
VAQFVFAGVA PKQITTNVLS AGIISAGASQ AGDMMHDLKA GYLIGVAPRK QFFAQIIGIF
VGIITCVPIY KLYDAAYDIG SASFPAPAAH AWKAVADVLS KGTNGLPANS VYGIIGGVVF
GILLTVFYKV VHILKPEKAQ YIPSALAFGI GMIVPPKQSI TMFIGALLFT VWKQRWPETN
SKYFFAVSSG LIAGEGIMGI FTALLKLAGL KAVVELGY
//
