ID D2VBI2_NAEGR Unreviewed; 263 AA.
AC D2VBI2;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC45911.1};
GN ORFNames=NAEGRDRAFT_66226 {ECO:0000313|EMBL:EFC45911.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC45911.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC45911.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; GG738861; EFC45911.1; -; Genomic_DNA.
DR RefSeq; XP_002678655.1; XM_002678609.1.
DR AlphaFoldDB; D2VBI2; -.
DR STRING; 5762.D2VBI2; -.
DR EnsemblProtists; EFC45911; EFC45911; NAEGRDRAFT_66226.
DR GeneID; 8850525; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_66226; -.
DR eggNOG; KOG0082; Eukaryota.
DR InParanoid; D2VBI2; -.
DR OrthoDB; 5517111at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0019001; F:guanyl nucleotide binding; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
SQ SEQUENCE 263 AA; 31219 MW; F627BC81ACD9AAA9 CRC64;
MWLLVKLWNC PFFKEYYESN WAKNAMLYEN VEEFVTRIER KKIFDPFSLI KLRSSGITSY
RTIWNNSNVE FLDAFGRRSE RRKWIYCIEN IKILIYTVSL SEFNLVEYNN VEVMNDSLEM
IGKLFGNGLL SDARKVILFT KPDILVKKLQ KRMEYSRKIN SVVRPELEII SNDYNERIVI
NSIITEYLER VSFHLDSYHI VNVTSEEEVR SVTELIFDNV TTPFISPCLL PITNRMITTM
YNIYLRKLLT DIQIITTINE LSP
//
