ID D2VDI6_NAEGR Unreviewed; 550 AA.
AC D2VDI6;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC45148.1};
GN ORFNames=NAEGRDRAFT_48621 {ECO:0000313|EMBL:EFC45148.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC45148.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC45148.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GG738864; EFC45148.1; -; Genomic_DNA.
DR RefSeq; XP_002677892.1; XM_002677846.1.
DR AlphaFoldDB; D2VDI6; -.
DR STRING; 5762.D2VDI6; -.
DR EnsemblProtists; EFC45148; EFC45148; NAEGRDRAFT_48621.
DR GeneID; 8850371; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_48621; -.
DR eggNOG; KOG1225; Eukaryota.
DR InParanoid; D2VDI6; -.
DR OrthoDB; 5475408at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.90.10.10; Bulb-type lectin domain; 1.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR036426; Bulb-type_lectin_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR PANTHER; PTHR14949:SF50; 3-PHYTASE; 1.
DR PANTHER; PTHR14949; EGF-LIKE-DOMAIN, MULTIPLE 7, 8; 1.
DR Pfam; PF07974; EGF_2; 5.
DR SMART; SM00181; EGF; 8.
DR SUPFAM; SSF51110; alpha-D-mannose-specific plant lectins; 1.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..550
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003038576"
FT DOMAIN 231..270
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 309..348
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 387..426
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 260..269
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 338..347
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 416..425
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 550 AA; 58646 MW; 0CD141EC1A032196 CRC64;
MKSATGILCF ICLLTLLILK ADYTLQQFTC FGLDPTDLSV CGGNGFCTAQ DTCDCQDLSY
GGYIHSNING TLNRLVKIAN APRNEHLVLQ LDANLILFSD TAGLPDWASG TYSPLNSDRY
MRIDNSTGAF TLHKLDGTVY ATVSSGCNGG IGPFRLVVRS DRNLAIYDSI GKICWIIDKY
PHIGSVMYHG AKCDVPICFD KNATEVCSGR GYCNVPHNCT CMEGAFGYDC RNFTCFGLAI
NDTSVCSGHG QCNNLNNCTC NDGYFGSKCQ EFNCNGIHYK ESSVCSGKGV CSSPNVCNCT
QGYSGAYCQE YYCDGTLYND QNVCSGHGKC NAPDSCSCSA GYSGATCLDY TCYGIHYADQ
TVCSGRGKCI GPDGCTCPTD FSGTSCQDYY CNGIHYKESN VCNGRGVCSA PTICNCTQGY
TGTYCQDFNC NGTYYSDAKV CSGNGKCNAP DSCSCSAGFS GATCQDFYCN GILSNDEKVC
SGNGKCASPN NCVCSPQFRG VSCETKVPST VASLSGNVIG KVNSSISIKK VSTLQMIFIL
ACVMICAILF
//
