ID D2VFX3_NAEGR Unreviewed; 507 AA.
AC D2VFX3;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=F-box domain-containing protein {ECO:0000259|PROSITE:PS50181};
GN ORFNames=NAEGRDRAFT_67776 {ECO:0000313|EMBL:EFC44155.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC44155.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC44155.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738869; EFC44155.1; -; Genomic_DNA.
DR RefSeq; XP_002676899.1; XM_002676853.1.
DR AlphaFoldDB; D2VFX3; -.
DR EnsemblProtists; EFC44155; EFC44155; NAEGRDRAFT_67776.
DR GeneID; 8848075; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_67776; -.
DR InParanoid; D2VFX3; -.
DR OrthoDB; 1329630at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1280.50; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR Pfam; PF12937; F-box-like; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..82
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 100..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 57709 MW; 45DAD47AA68E7CB1 CRC64;
MAEFSIIKSS RHEENFNSVD VRNGFSSNQQ QLEWENVDKV YLPPEILLEI LQFMDFDAIV
MTSATCRGFY EVSHDDELWR KLLSADWKLL KDDAAAALNN HQNTNQNGGS LLSSPVANNT
NSSRDEAASS SSSPNSYELL DQNNSGDLYE KYKERYLRYK KWRDSIAFIY SEERNQYINN
VETQTSGKFV GYLKYFLSFP ILFYRLLIFL FISQDEQPDF GLAHEIEYIQ EKSLRAGGSL
LLLIIFAPML FCTWMIGELP ATPFYATLHV FFKMVFTILC IAAHFYNRMD RNIEFYKEAN
SVSLVIILQT ILTLILMRYV DDFIICCLIS FNMSTALGLA ISLKHMIKNT ESIEGLFESS
NTPAQHYLSP LFEIFRNRSV VTNLILSNLM ILVIMIGGFK TFVWILIFIA IAIVTGTSGG
SGGVDSLDRR MLIFVLVIFA CISISALATS IIGGNYKRKS KARNTSAVLL LVILTMSFIT
LAMRVISIKS GETERWQLSL FDITDEE
//
