ID D2VHJ4_NAEGR Unreviewed; 410 AA.
AC D2VHJ4;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Rho family small GTPase {ECO:0000313|EMBL:EFC43598.1};
GN ORFNames=NAEGRDRAFT_68347 {ECO:0000313|EMBL:EFC43598.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC43598.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC43598.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738872; EFC43598.1; -; Genomic_DNA.
DR RefSeq; XP_002676342.1; XM_002676296.1.
DR AlphaFoldDB; D2VHJ4; -.
DR STRING; 5762.D2VHJ4; -.
DR EnsemblProtists; EFC43598; EFC43598; NAEGRDRAFT_68347.
DR GeneID; 8862193; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_68347; -.
DR eggNOG; KOG0393; Eukaryota.
DR InParanoid; D2VHJ4; -.
DR OrthoDB; 5506562at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR003578; Small_GTPase_Rho.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24072; RHO FAMILY GTPASE; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
SQ SEQUENCE 410 AA; 48212 MW; 6BB968D096C3F882 CRC64;
MSVIDDDNFF LLENRLDQAS IICILEFLNR NEINNLASLI YRSDSTEIEK GFYNETYLDL
KFGNCLMIYC WKDEFWEDYM NEKIMRINKL LRKSITPIEI FNDDDWNDGG NIRLKFIKYM
WKRIGSENWR LIQKTRHDRK LYIHSLSDKL SKIAKLNKRF KTPECEGLIR ERIEQACFIE
EDSLSKYLKE PMIVDNLNES IQYEKWVSMG MNVGKTSLFM TISGVEFPFE YTPKVFDGYN
AAVLVSCINK KGEERKVSFH FGFWDTVGNE EYDKLRPLGY PDTTIFTLNY AINDWSSLKQ
LAEHLLWEST LSEPNATFVV VSTKNDLKEE CYWNSLLDPL LMEEAISPED GIMFTKSIGA
ISFIETSSKT KKGIEYLLQK LVLLRLIHLQ HLKSIEKQKQ DDTKRKCSVQ
//
