ID D2VHY7_NAEGR Unreviewed; 926 AA.
AC D2VHY7;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC43500.1};
GN ORFNames=NAEGRDRAFT_68491 {ECO:0000313|EMBL:EFC43500.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC43500.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC43500.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738873; EFC43500.1; -; Genomic_DNA.
DR RefSeq; XP_002676244.1; XM_002676198.1.
DR AlphaFoldDB; D2VHY7; -.
DR STRING; 5762.D2VHY7; -.
DR EnsemblProtists; EFC43500; EFC43500; NAEGRDRAFT_68491.
DR GeneID; 8853380; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_68491; -.
DR eggNOG; ENOG502QU61; Eukaryota.
DR InParanoid; D2VHY7; -.
DR OrthoDB; 5491190at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14499:SF125; GH08630P; 1.
DR PANTHER; PTHR14499; POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 2.
DR SUPFAM; SSF54695; POZ domain; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 178..308
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT DOMAIN 402..498
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 142..172
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 313..375
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 8..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 108132 MW; AED6A76B91DB0D8C CRC64;
MYSSGEDSDE WESDRSFHPS EEDDDSDDYD DDYRRNNSDY YYCSSCGTYH PHNNSTTLNT
KPFGWAGASA FSKDDLLFQH PIFTILEDAK RPTQGSALVR NYVKRSMQAY WAKQREESNN
KEETEASSSI VNNVHQVDRE LLEKAKIELL KYERKEKQSD ELVEEIIKFN LEETDNTTFL
ELNIDGKIYK TTRKTMMKYD SLIKVMIENK ESGGFDIETD SAGRVVFRSV PHSDYFKHIL
IFFRGDDEEI TPSDKELSDE ITSTMRKKFK FITEGFNLAN YLEFHEICNY FCVKDLLTLI
EKKVENFENP LGLEVLSEKY RHIEQEKEEY YKKVKANEKA ISQADEKIRE LIKQLRSMEE
KKSKLLVEKL RLKKEQDLIS KLVEMKASFK NEDAKSTSVE EFDIVFNIGG EDFAFKSTEL
LKYESSLLYK LMNKSQDKKS IFLDRDPSMF SYIYKFIKNE TIPTGLANQK QIKLIEESKF
FGIDALTVKI DIFRYPVEDL SEEDREIRET ESILRKLFSY DRQNPLIDDP FVNLISVFDN
VTDFYPVEQP TLTNMLFDFE NNSELHGKEI PIIATGKEEF DFNFKSFTAN IFEELDWNGV
FIAGGAIQTC CKAHASMYNK KIAATMLQSS QDIDIFLYGL TKSEAEDKIR HIYSLVKKVK
KDNFIVVRTK YTVTFCAPGI PAIQVVTRLY KSCAEVLIGF DIDSCCVGYD GNKVWCLPRF
RRAFTRRYNL VDIERQSLTY ELRLRKYAYR GFRVMVPGYK PELVKKPGLL SHSYYWKQSD
LNGLALLLYY QADTSVINPF TAKRNDNISI SSESTDSEEE QEGKHSDYGD FFCHKIMSYP
FPYMMISYKN FIQKHKCHFV CALNDVESII DSKDILTSNH TISPTIEWIT EQPHRQLLGS
LFPVFDNFYV CAYDAHYRKK KDSSLY
//
