ID D2VI60_NAEGR Unreviewed; 433 AA.
AC D2VI60;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC43535.1};
GN ORFNames=NAEGRDRAFT_49744 {ECO:0000313|EMBL:EFC43535.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC43535.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC43535.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738873; EFC43535.1; -; Genomic_DNA.
DR RefSeq; XP_002676279.1; XM_002676233.1.
DR AlphaFoldDB; D2VI60; -.
DR STRING; 5762.D2VI60; -.
DR EnsemblProtists; EFC43535; EFC43535; NAEGRDRAFT_49744.
DR GeneID; 8853115; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_49744; -.
DR eggNOG; KOG0396; Eukaryota.
DR InParanoid; D2VI60; -.
DR OMA; KHAECTF; -.
DR OrthoDB; 1429623at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd16659; RING-Ubox_Emp; 1.
DR InterPro; IPR013144; CRA_dom.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR045098; Fyv10_fam.
DR PANTHER; PTHR12170:SF2; E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA; 1.
DR PANTHER; PTHR12170; MACROPHAGE ERYTHROBLAST ATTACHER-RELATED; 1.
DR Pfam; PF10607; CTLH; 1.
DR SMART; SM00757; CRA; 1.
DR SMART; SM00668; CTLH; 1.
DR PROSITE; PS50897; CTLH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 174..231
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT COILED 35..90
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 433 AA; 49605 MW; 6D876A15279B4AAE CRC64;
MSSSLSHSTS KELESEHDLL QVPFEMLNFE FRSSQKSVEK DLSILEKAMK EMLQKASKQN
LSIQDQTNFL DKVVTKLRGV KRKLEETNIE ETQLLNTCKD RIDHLNEYPL IDGAISRRKS
TSNIDDNQYR TLSNWRRVRV SRVLVDYLLR FGHYETALAL ADSEKIKHLV NTQVFIQIRG
IIEGLKNNDC GPALKWCSEN RSRLRKISSN IEFDLRVQEF IELSKQDKKM EAVIHARKYL
TNPIVDKGNS SAATTTNEDD NSCKITPEQT NTVKKIMAAL AFGPKTLMAG YKELYDDKRW
DELVEEFNKE NYKLYGMTEE ATLFKLLKAG LSALKTPYSY DENSINVNDP LSHPLFKELA
KDLPFAHHHH SKLVCSICGD IMDHLNPPLV FPNGNVYSQK GVAENMAKNN GTFVDPRDGK
SFQEEDGKKL FIM
//
