ID   D2VK05_NAEGR            Unreviewed;       592 AA.
AC   D2VK05;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC42864.1};
GN   ORFNames=NAEGRDRAFT_50183 {ECO:0000313|EMBL:EFC42864.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC   Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC42864.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC42864.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA   Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA   Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA   Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
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DR   EMBL; GG738877; EFC42864.1; -; Genomic_DNA.
DR   RefSeq; XP_002675608.1; XM_002675562.1.
DR   AlphaFoldDB; D2VK05; -.
DR   EnsemblProtists; EFC42864; EFC42864; NAEGRDRAFT_50183.
DR   GeneID; 8862855; -.
DR   VEuPathDB; AmoebaDB:NAEGRDRAFT_50183; -.
DR   eggNOG; KOG0379; Eukaryota.
DR   InParanoid; D2VK05; -.
DR   OMA; SRPANCE; -.
DR   OrthoDB; 5477547at2759; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   PANTHER; PTHR23244; KELCH REPEAT DOMAIN; 1.
DR   PANTHER; PTHR23244:SF471; KELCH REPEAT-CONTAINING PROTEIN 1-RELATED; 1.
DR   Pfam; PF01344; Kelch_1; 1.
DR   Pfam; PF13415; Kelch_3; 2.
DR   SMART; SM00612; Kelch; 2.
DR   SUPFAM; SSF117281; Kelch motif; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          505..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        505..532
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        552..592
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   592 AA;  66033 MW;  C52D64FFB4FDF42E CRC64;
     MSVVSEEAPV SVLPEESTTM LQSSSATTSI VTEEVPSTTT CEISDSTTVS IDNIPTRTTE
     TTSSDSNIVV INVEGEGPAN FLQRAIAVAN KVYIYGGENS SGFWTNSLTI LEGESNKRIS
     WKKPRCFDFP PKTDSHSLVV FENNMIIFGG TDNQWINGGN NCIYCLDLEK LEWAVAPENA
     DQDTTLVPQG RKQHSTAAVA NKMYIFGGIS SQVGSESVFN DVFVFDNETK LWSKVMVNGD
     SPTPRSGHTM VYNQQTDSLV IFGGKVGGSY SNEVWSLSLS ELSWTSMSTT GNIPCGRENH
     SSVVCNDSMI IYGGWNIGGP KNDLYSLNLA TFEWKKYSHN LETEKDSKRF GHASVYLDGS
     VLIFGGKNHL FNNQEAILKI NMNNCAEVPV ETEKPKEKKD IEEIILDLDE KDVVLYKNIF
     DQLTEENIKQ YEELNTMLLK QKLFSAQVES LIESNRTLMA KEFTTPPSYT ESSVPIIYSE
     VVETPQSYKD LMGQVFQPVV EQKQTELKEE GNNTDSNNEE IKEVEQKPKL PEDIPVIVDL
     PSIPESPHIL EVAEEPMVEE KLENTNNIED NKIENKEETT ETATESNNQR DE
//