ID D2VSP4_NAEGR Unreviewed; 283 AA.
AC D2VSP4;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC40159.1};
GN ORFNames=NAEGRDRAFT_81095 {ECO:0000313|EMBL:EFC40159.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC40159.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC40159.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738894; EFC40159.1; -; Genomic_DNA.
DR RefSeq; XP_002672903.1; XM_002672857.1.
DR AlphaFoldDB; D2VSP4; -.
DR EnsemblProtists; EFC40159; EFC40159; NAEGRDRAFT_81095.
DR GeneID; 8854683; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_81095; -.
DR InParanoid; D2VSP4; -.
DR OrthoDB; 5483176at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.550; Membrane associated eicosanoid/glutathione metabolism-like domain; 1.
DR InterPro; IPR023352; MAPEG-like_dom_sf.
DR InterPro; IPR001129; Membr-assoc_MAPEG.
DR PANTHER; PTHR35371:SF1; BLR7753 PROTEIN; 1.
DR PANTHER; PTHR35371; INNER MEMBRANE PROTEIN; 1.
DR Pfam; PF01124; MAPEG; 1.
DR SUPFAM; SSF161084; MAPEG domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 283 AA; 31446 MW; 53100C5539B6827E CRC64;
MSKKQTTEKK SEPTVEKTTV TSVGKSTKEV VKGKSWGRII FSSYITLVVL LILFLILHLA
HNHLVYQSNL VTQHDSRLKR LYKEGERAAP LFSQNVNVLP PAIVNPINQV IRLINDNPKV
KELNINIPLF PINEFVEINI RVSSIPFIAL LIAFAYTMTS KVPVILGQII EGNGKLDNDT
PREQQSKLTG FGSRALGAHN NAFEALIGFG IIVAVTLLRI NGDSSERASL LALSLVKESI
CFIAARTVFQ IVYVLGFPGF IRTLVWAFGW ISVLSLYIQN AVY
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