ID   D2VT03_NAEGR            Unreviewed;       982 AA.
AC   D2VT03;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Enhancer of polycomb-like N-terminal domain-containing protein {ECO:0000259|Pfam:PF10513};
GN   ORFNames=NAEGRDRAFT_81121 {ECO:0000313|EMBL:EFC39996.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC   Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC39996.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC39996.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA   Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA   Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA   Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
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DR   EMBL; GG738895; EFC39996.1; -; Genomic_DNA.
DR   RefSeq; XP_002672740.1; XM_002672694.1.
DR   AlphaFoldDB; D2VT03; -.
DR   STRING; 5762.D2VT03; -.
DR   EnsemblProtists; EFC39996; EFC39996; NAEGRDRAFT_81121.
DR   GeneID; 8850981; -.
DR   VEuPathDB; AmoebaDB:NAEGRDRAFT_81121; -.
DR   InParanoid; D2VT03; -.
DR   OMA; KSANHHA; -.
DR   OrthoDB; 5398022at2759; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   InterPro; IPR019542; Enhancer_polycomb-like_N.
DR   Pfam; PF10513; EPL1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   DOMAIN          422..624
FT                   /note="Enhancer of polycomb-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10513"
FT   REGION          1..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          817..852
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          876..982
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..64
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..110
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        111..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..227
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..257
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..290
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..312
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..340
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..400
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        817..832
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        833..852
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        876..895
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        911..946
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   982 AA;  110470 MW;  0F87EF25B2AF0F17 CRC64;
     MPRKRSVSRK KKAPTTITDN DIDDNPEEEE QQQRDTASSS SSSEENNKES SAEETDKEKS
     TSNILKQQVD DNTMLTDEDG ASTANNTSVV LDPNDHDLSS SDEGKEDEIN HPTTTSPLFR
     RRTSTANKNN NHRQSSSSSP PEETDPTSPS SPSTLQIANH SPSKTNTTTL ASNTITAATS
     EGNNHNSQDV LIKKTRTTRR KPLQSPITKK QDDNNTSDND EDKTTTIEQP SESSNESSST
     STAAADTTTS LAEEDNTNNN QMEDDDAFLT HKSDYDSDEV IIETPKKTRA NKRGRTPLPK
     STTKDTDEPK STEEATITTS TTSEPSADEK EQKEMDTTEE DTTTTSVVKR TPTRTRITKS
     TKRKAAAAAS SSESDSDNES TKGKSKQRKL DSRPQRKRGM ETPVSQRCNP TTPQPSPGLA
     RPRKLDVSKK LLILRGSDLK NLASLKKKVT AAINEAKKAA NKASPKRPDS DVSRLSGNLT
     DLDLKLLTDE SISTGTVTLI DSTSQSNKRY FRDADEYDEF KEFRDGTMIH IDIPNVRIIE
     EEPAGPPFKR TSEFIKYEDP DRYDRSTLTL NPIPAQADFD MYSHRKIDIS VEYNIESEDE
     EWLNNYNKDS RYPLSEKDFE SIIALMNRAS KNGKSCWFSV ASVIELSRFF DVRLEERHIV
     QVKKLWESKY NPQHKLFKSE ELQKRIENEN LLYEYMCVKQ QLNTYKERVE QIMGISEQKK
     ELLDKHSKLM KRKNYSVTKD FPKFVTKYSK LTYDEETETN SDDDESGDIS NKLEEEQILK
     DSFPADQVEI ELFIAEEKKE EEERKKSNQK VTKSWKNKGC DNLEEQHDES TLESTEFNSS
     SNEPYSPLSS VPSSLASLII PPLPPILTKN LSNIQTPEST STNIDTPTSA ISNSDDLHST
     KRRTRKKRMD SGTPTSNVSR TPTSASNMDF QQSFDESSSL ISSPTPSDIV PPLLEASSPL
     PSPNNNGNMM RRRKKRSKIV IN
//