ID   D2VT71_NAEGR            Unreviewed;       473 AA.
AC   D2VT71;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC40033.1};
GN   ORFNames=NAEGRDRAFT_52059 {ECO:0000313|EMBL:EFC40033.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC   Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC40033.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC40033.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA   Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA   Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA   Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
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DR   EMBL; GG738895; EFC40033.1; -; Genomic_DNA.
DR   RefSeq; XP_002672777.1; XM_002672731.1.
DR   AlphaFoldDB; D2VT71; -.
DR   STRING; 5762.D2VT71; -.
DR   EnsemblProtists; EFC40033; EFC40033; NAEGRDRAFT_52059.
DR   GeneID; 8854190; -.
DR   VEuPathDB; AmoebaDB:NAEGRDRAFT_52059; -.
DR   eggNOG; ENOG502S7Y1; Eukaryota.
DR   InParanoid; D2VT71; -.
DR   OrthoDB; 5482859at2759; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00130; PAS; 2.
DR   CDD; cd05992; PB1; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR000270; PB1_dom.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR31600; TINY MACROCYSTS PROTEIN B-RELATED; 1.
DR   PANTHER; PTHR31600:SF2; TINY MACROCYSTS PROTEIN B-RELATED; 1.
DR   Pfam; PF00989; PAS; 2.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00666; PB1; 1.
DR   SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   DOMAIN          232..279
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          347..417
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          37..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   473 AA;  52944 MW;  BB47407108B94324 CRC64;
     MNQLQVTKLG HRKKFKKLVE ALKKNSNITN FLETLSENDS DMIPPTSSSS SSNNINNNNN
     GTASNSTGGG GNFTQTAQPS NFQNSNLSEL SAGSSGGGVS ADLVFKCYHA EDVHLIALKR
     DRATFSELKL KIIEEYNCLK PIIKYRDTEG DFINIRKEED FNICKQNVPV DSAIRLYITT
     ENDADDTSSQ TSGSEMSSSN TAQLHAQRHT DQFPSIYASD EEPEMDDGAV FFDDFVDSVI
     IITDDKIVQY MNKSAEKAFG YTKKEVIGRN VKILMSNTHR IQHDNYVDNY LRTGQAKIIG
     SGRMVEARAK DGLIFPIWLS VAESAWLGRH AFTATIQDLR KDKSKHSNSS VTSLLENLVD
     AVIIIDLKCN ICFLNKSSEK MFGYNRDELI GKNIKQLMPE KYSINHDSYV SHYLETGEKK
     VIGRGRKVTA KDKSGSMFPI WLSVSETKFS GERSFVGTIQ DLRKENSLDK MLH
//