ID D2VTD2_NAEGR Unreviewed; 419 AA.
AC D2VTD2;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=ZZ-type domain-containing protein {ECO:0000259|PROSITE:PS50135};
GN ORFNames=NAEGRDRAFT_81162 {ECO:0000313|EMBL:EFC39910.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC39910.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC39910.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738896; EFC39910.1; -; Genomic_DNA.
DR RefSeq; XP_002672654.1; XM_002672608.1.
DR AlphaFoldDB; D2VTD2; -.
DR EnsemblProtists; EFC39910; EFC39910; NAEGRDRAFT_81162.
DR GeneID; 8854325; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_81162; -.
DR eggNOG; KOG1426; Eukaryota.
DR InParanoid; D2VTD2; -.
DR OrthoDB; 1329809at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd14319; UBA_NBR1; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR20930; OVARIAN CARCINOMA ANTIGEN CA125-RELATED; 1.
DR PANTHER; PTHR20930:SF0; PROTEIN ILRUN; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 238..295
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
SQ SEQUENCE 419 AA; 48263 MW; 1EF2588AB9FCFC94 CRC64;
MSFPSSHLIY HPILANNNTN GQQVPMPQHQ QQLPNLHNIF QPAQQQPKPI HVKVLVFETK
KEDLSALETL KPTSIRRGER VLTNYADLTR YLTEKCGLTL ENALIRYQDD ENHWVDISSD
EELAYGIQLC RESRTSAIRS VFRIAVILLK KEEEKPRQPE EEKRECPYWK GRRQGGCPFR
RPRHHPLPEN HPHCPFMFKK TMDGDNVLEV DIDVEQLKNG LNVNDFVREN IDKVQVPHFG
VTCDGCGKYA FVGKRFKCDD CDDFDFCEDC FASETVRNAH FGGSHSFTEQ QPRSACFLRN
IFGAEKKEEE TVIDNQLYEE QPVVVEEPVE EPVVVEEPVI VPEPVNVYQV PHPLNPIQQP
IVEEPVVVVQ EPIVQPQPTL YQTELALLRD MGFVDEVSNL ILLNKYNGDL QRVIVDLIH
//
