ID D2VVI6_NAEGR Unreviewed; 946 AA.
AC D2VVI6;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC39040.1};
GN ORFNames=NAEGRDRAFT_52596 {ECO:0000313|EMBL:EFC39040.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC39040.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC39040.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738902; EFC39040.1; -; Genomic_DNA.
DR RefSeq; XP_002671784.1; XM_002671738.1.
DR AlphaFoldDB; D2VVI6; -.
DR EnsemblProtists; EFC39040; EFC39040; NAEGRDRAFT_52596.
DR GeneID; 8858155; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_52596; -.
DR InParanoid; D2VVI6; -.
DR OrthoDB; 232416at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR CDD; cd16448; RING-H2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 234..278
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 55..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..327
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 946 AA; 108623 MW; 2C5F01ED406B49DB CRC64;
MSQHSVEFDL FKDELIDDHC MDDVIIEGNF SDRLDILKDY LSALQELKQQ VQIFASSSQS
QPSSTSHQEE DDSVHIPSIQ QQAPPKPKQY VTISKLINPK EYYLNQTNSF SDLMIKARVR
IPLDQIIAKY QIKNKDLMII PFSTLSMTSL LFHDVHFEYY QAVAVEENTE MDCNEDIRSI
IQENNNAKTS IVEEIEEVEM VDNCSHCSSS SEEVEVGNNQ IEKKEAFVDI NCDCGICLLP
LYDGTQIYNL ESCNHAFHLA CVHRCMESRN IQKCCVKCFK EISQDEKKQI KLLFKEEVRT
KRIEKRVSNN PKPKDKPKKE KLKPKIQEPS FEPPSTPHKI NHNLIIEEYG YMLNNHSELP
LNYKCKSYLP AFKRSDKPIE LICTITLNPN FGKDAHIFLL RIESSILPKS LKSFNFEELT
EKIKEQLEDK TSKRIENAKE YFGLKNKKVT SIIDKIRDCE FFYRTATEIR ENSLTFNSPI
IVGKPNEPIV IPDSSHLKRK EPPKEPTLDF IPVKKRKCDL APFRIDRSQF MDISILLDTD
YSSIDMVISY LENYHGIQST RSLLKGLTEY SLTESDCDIV SKLYLLLQHY DLSCSRGIHS
LYDVFKECDV KLSSILDLYD VLSQSVNLFP NDIIYQYAKN TKEANMSTIS LINIASKFLL
PKYSETEIIK ACTNIVDLSN NFFTSLDASI IISSSCEHEI LYGLFNVVKS IDYFIVENMD
LQTVLLNLIT IIDHIERTGI EAIRKCLLKS YGIDEDKERD ENQMVIDTVN EQEKEQSNSN
EVIDAPVEIN MNLMDSQMGD ESPEQQQFNA DIVPPFKESP KQSPNSTISI PSFKISKEIP
LTQTSISIHS SGKKPEPVTQ NRSDLTSIAE CSIEEKELVK NISQQLSQIS SIHLSEPQTK
LIVIPHSQES FPIDFSYHIE ENEEKISLSL SSFESEKVPS IFPYFD
//
