ID   D2VWX2_NAEGR            Unreviewed;       329 AA.
AC   D2VWX2;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=UBC core domain-containing protein {ECO:0000259|PROSITE:PS50127};
GN   ORFNames=NAEGRDRAFT_81521 {ECO:0000313|EMBL:EFC38765.1};
OS   Naegleria gruberi (Amoeba).
OC   Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC   Vahlkampfiidae; Naegleria.
OX   NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN   [1] {ECO:0000313|EMBL:EFC38765.1, ECO:0000313|Proteomes:UP000006671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEG-M {ECO:0000313|EMBL:EFC38765.1,
RC   ECO:0000313|Proteomes:UP000006671};
RX   PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA   Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA   Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA   Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA   Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT   "The genome of Naegleria gruberi illuminates early eukaryotic
RT   versatility.";
RL   Cell 140:631-642(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GG738905; EFC38765.1; -; Genomic_DNA.
DR   RefSeq; XP_002671509.1; XM_002671463.1.
DR   AlphaFoldDB; D2VWX2; -.
DR   STRING; 5762.D2VWX2; -.
DR   EnsemblProtists; EFC38765; EFC38765; NAEGRDRAFT_81521.
DR   GeneID; 8858596; -.
DR   VEuPathDB; AmoebaDB:NAEGRDRAFT_81521; -.
DR   eggNOG; KOG0897; Eukaryota.
DR   InParanoid; D2VWX2; -.
DR   OMA; FAFRTGH; -.
DR   OrthoDB; 37924at2759; -.
DR   Proteomes; UP000006671; Unassembled WGS sequence.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   PANTHER; PTHR24067; UBIQUITIN-CONJUGATING ENZYME E2; 1.
DR   Pfam; PF00179; UQ_con; 1.
DR   SMART; SM00212; UBCc; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT   DOMAIN          165..329
FT                   /note="UBC core"
FT                   /evidence="ECO:0000259|PROSITE:PS50127"
SQ   SEQUENCE   329 AA;  37280 MW;  DB85DB429B36F68A CRC64;
     MSLKAEAEKF INNPKENSFS WTLKSNSTDE KIIVIVDSEV DAEDNPYFSV TKNGDSFKVT
     SQYYLLEEVG DVKFVKSLSD YCGSGKRSLT DILQKATALY KEVESALLGD EDGGDEEPEE
     VEIDIGDDMD DDPIQPVTHQ SSGGYDPEFE EMKKKFKKPT GASEGCVNCI MKEYMKIKQA
     NTEKFGISAN PVNDDLFHWE IRFFNFDIKE DGKIAKDLQE YKKKNGIDYI TLDLTFPLEF
     PFKPPFIRVL KPRFAFRTGH VTIGGSICME LLTSSGWSSV CSLESIFVQI RSEMVAGEAQ
     LDFSNTSPYS EHEAKEAFFR VAQRYGWEK
//