ID D2W171_NAEGR Unreviewed; 660 AA.
AC D2W171;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC37131.1};
GN ORFNames=NAEGRDRAFT_82002 {ECO:0000313|EMBL:EFC37131.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC37131.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC37131.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738921; EFC37131.1; -; Genomic_DNA.
DR RefSeq; XP_002669875.1; XM_002669829.1.
DR AlphaFoldDB; D2W171; -.
DR STRING; 5762.D2W171; -.
DR EnsemblProtists; EFC37131; EFC37131; NAEGRDRAFT_82002.
DR GeneID; 8856810; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_82002; -.
DR eggNOG; KOG2314; Eukaryota.
DR InParanoid; D2W171; -.
DR OMA; LWGGPQF; -.
DR OrthoDB; 5479191at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR CDD; cd12278; RRM_eIF3B; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011400; EIF3B.
DR InterPro; IPR034363; eIF3B_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR14068; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED; 1.
DR PANTHER; PTHR14068:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B; 1.
DR Pfam; PF08662; eIF2A; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 36..120
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 660 AA; 75907 MW; C4A6F11CEDF39A49 CRC64;
MSKQYIVTPR DIQNFDENEE FVFDEPEVTF NDDISNVVVI DGLPIIDQAK EEALKSKVVQ
IIEKKAEAKI VNFYIPYQAG KSKGMAIVEL STAEQAKKVL DGIEGFKFAS FTLHSISAAE
VDKYQKFDET TYQQQHKQQS KQYKERDNLV SWLKDPNARS QYAIRYDETV DICWNDPLHV
KEIIYSKERW SDDKIDFSPL GSYIVTYHEK GVALWGGPEF KDQDTLSHRN VISVQFSPNE
SFVVTVSESP ARAVLWDLRA QRKAMSLPLK DRSALKGHVF KWSADEKYFA KMGVDCIHIF
DSSTMELLHQ KTYSVPGVRD FAFNPVGKSF MIYSAINDTN GEGLVTLVDI NSRSIKELKS
KPYYNSTDIK LNWQLSGDYI AIATSRESTI QMEKVITTAF DVMKVNQKNF PIEGIADFND
CVDEFEFEPI GDTLAIIHGP GNVKKSFSLY SFKNAVHKLI KKCEGKTINR MLWSPRGHDL
VLMNTKLVSV TLEFWNAEEG ELVGTGEHFS MTDACWDPSG RYFSTFVSAE RRSNDNGFII
WTFLGKVMHK ANVERLLEFK WRPRIKSLLT ANMEKEVKKR LPNKKVEIEQ KLLQEAKALR
EAKLKKRKSA WDEFEQVLAR LKSQYEKMKP ELIALKGYDP DEFNQEEVDE VIETIEEIVE
//
