ID D2W3A4_NAEGR Unreviewed; 324 AA.
AC D2W3A4;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EFC36482.1};
GN ORFNames=NAEGRDRAFT_54379 {ECO:0000313|EMBL:EFC36482.1};
OS Naegleria gruberi (Amoeba).
OC Eukaryota; Discoba; Heterolobosea; Tetramitia; Eutetramitia;
OC Vahlkampfiidae; Naegleria.
OX NCBI_TaxID=5762 {ECO:0000313|Proteomes:UP000006671};
RN [1] {ECO:0000313|EMBL:EFC36482.1, ECO:0000313|Proteomes:UP000006671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEG-M {ECO:0000313|EMBL:EFC36482.1,
RC ECO:0000313|Proteomes:UP000006671};
RX PubMed=20211133; DOI=10.1016/j.cell.2010.01.032;
RA Fritz-Laylin L.K., Prochnik S.E., Ginger M.L., Dacks J.B., Carpenter M.L.,
RA Field M.C., Kuo A., Paredez A., Chapman J., Pham J., Shu S., Neupane R.,
RA Cipriano M., Mancuso J., Tu H., Salamov A., Lindquist E., Shapiro H.,
RA Lucas S., Grigoriev I.V., Cande W.Z., Fulton C., Rokhsar D.S., Dawson S.C.;
RT "The genome of Naegleria gruberi illuminates early eukaryotic
RT versatility.";
RL Cell 140:631-642(2010).
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DR EMBL; GG738930; EFC36482.1; -; Genomic_DNA.
DR RefSeq; XP_002669226.1; XM_002669180.1.
DR AlphaFoldDB; D2W3A4; -.
DR EnsemblProtists; EFC36482; EFC36482; NAEGRDRAFT_54379.
DR GeneID; 8862522; -.
DR VEuPathDB; AmoebaDB:NAEGRDRAFT_54379; -.
DR InParanoid; D2W3A4; -.
DR OrthoDB; 5477371at2759; -.
DR Proteomes; UP000006671; Unassembled WGS sequence.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006671}.
FT DOMAIN 72..219
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|Pfam:PF00211"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 324 AA; 37383 MW; 9B75B0D9C43AC54E CRC64;
MTSDSVELEK SQPFSSIEDN SLEGGKASKL SNILDSKKKS SKLKCKFSLY LEPRKISINQ
MYIEGLNEWL LSLEGNPTHL VSLLGDLFSQ VDTVIRTTSG HLVNFENDIL TIAYNTTINQ
NNHEEKAVAS AQLLQEKLTN VKENKWRESG LLREEICELI NFRFAICAQK TFCGNIGTKD
IKHFTIFSST RHNLDQIIRF GKKLKVPIII TQHIKQYCHT RCETRFLDRR ELREDYFFSS
LDDFNQENWE IGSVSMSNSL TKDCLLYELG DSIEMKQETD DGKFEEAIPL FREYQQVNPN
DLPTQHLLRL CEQQAQTPTL NILE
//
