ID D2ZWW4_NEIMU Unreviewed; 182 AA.
AC D2ZWW4;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Oligoribonuclease {ECO:0000256|HAMAP-Rule:MF_00045};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00045};
GN Name=orn {ECO:0000256|HAMAP-Rule:MF_00045};
GN ORFNames=NEIMUCOT_05112 {ECO:0000313|EMBL:EFC88440.1};
OS Neisseria mucosa ATCC 25996.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=546266 {ECO:0000313|EMBL:EFC88440.1, ECO:0000313|Proteomes:UP000003344};
RN [1] {ECO:0000313|EMBL:EFC88440.1, ECO:0000313|Proteomes:UP000003344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25996 {ECO:0000313|EMBL:EFC88440.1,
RC ECO:0000313|Proteomes:UP000003344};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: 3'-to-5' exoribonuclease specific for small
CC oligoribonucleotides. {ECO:0000256|HAMAP-Rule:MF_00045}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00045}.
CC -!- SIMILARITY: Belongs to the oligoribonuclease family.
CC {ECO:0000256|ARBA:ARBA00009921, ECO:0000256|HAMAP-Rule:MF_00045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC88440.1}.
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DR EMBL; ACDX02000008; EFC88440.1; -; Genomic_DNA.
DR RefSeq; WP_003742860.1; NZ_ACDX02000008.1.
DR AlphaFoldDB; D2ZWW4; -.
DR STRING; 546266.NEIMUCOT_05112; -.
DR GeneID; 61323211; -.
DR eggNOG; COG1949; Bacteria.
DR Proteomes; UP000003344; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006259; P:DNA metabolic process; IEA:UniProt.
DR CDD; cd06135; Orn; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR HAMAP; MF_00045; Oligoribonuclease; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR022894; Oligoribonuclease.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR11046; OLIGORIBONUCLEASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11046:SF0; OLIGORIBONUCLEASE, MITOCHONDRIAL; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00045};
KW Exonuclease {ECO:0000256|HAMAP-Rule:MF_00045, ECO:0000313|EMBL:EFC88440.1};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_00045};
KW Nuclease {ECO:0000256|HAMAP-Rule:MF_00045};
KW Reference proteome {ECO:0000313|Proteomes:UP000003344}.
FT DOMAIN 7..180
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT ACT_SITE 129
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00045"
SQ SEQUENCE 182 AA; 21299 MW; E7BC881C5A91AB02 CRC64;
MTQNANNLCW LDMEMTGLDP ERERIIEVAM IITDSDLNVL AQSEVYVVHQ SDELLDGMDE
WNTATHGRTG LTRRVRESQL TEAEVEQKLL DFIAQWIPEK ATPMCGNSIH QDRRFMVKYM
PRLEAYFHYR NLDVSTLKEL AKRWNPPVAK GVVKRGSHQA LDDILESIEE MRYYRENFLK
LP
//
