ID D3CR61_9ACTN Unreviewed; 633 AA.
AC D3CR61;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:EFC86808.1};
GN ORFNames=FrEUN1fDRAFT_0059 {ECO:0000313|EMBL:EFC86808.1};
OS Parafrankia sp. EUN1f.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC Parafrankia.
OX NCBI_TaxID=102897 {ECO:0000313|EMBL:EFC86808.1, ECO:0000313|Proteomes:UP000004777};
RN [1] {ECO:0000313|EMBL:EFC86808.1, ECO:0000313|Proteomes:UP000004777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EUN1f {ECO:0000313|EMBL:EFC86808.1,
RC ECO:0000313|Proteomes:UP000004777};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Tice H., Bruce D., Goodwin L.,
RA Pitluck S., Larimer F., Land M.L., Hauser L., Beauchemin N., Sen A.,
RA Fernandez M., Tisa L.;
RT "The draft genome of Frankia sp. EUN1f.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC86808.1}.
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DR EMBL; ADGX01000001; EFC86808.1; -; Genomic_DNA.
DR RefSeq; WP_006537899.1; NZ_ADGX01000001.1.
DR AlphaFoldDB; D3CR61; -.
DR Proteomes; UP000004777; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EFC86808.1}.
FT DOMAIN 4..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 65..444
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 510..596
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 633 AA; 68643 MW; 1783C5BD0A48452F CRC64;
MGRYEDVFRA SVEDRERFWL NAAGALDWHR APTRALDDSN PPFYRWFADG EINVAHNALD
RHVEAGRGDQ AALIYDSPVT DTRRTYTYTQ LRDEVATFAG VLRGLGVGLG DRVVIYMPMI
PEAAIAMLAC ARLGAVHSVV FGGFAAKELA ARIDDAAPKV VVSASCGIEG RRIIEYKPLL
DKAIELSANK PQTQVILQRP QAVAAMGPND ADWAEAAASA TPADPVTVKS TDPLYVLYTS
GTTGRPKGVV RDSGGYATAL AWSMPNVYDV GPGQTIFTAS DVGWVVGHSY IVYAPLLAGA
TTVLYEGKPV GTPDAGQFWR VMSEYGVRSM FTAPTAFRAL RKEDPNGDYA RRYDLSGLRY
LFLAGERLDP ETYRWASELL KIPVIDHWWQ TETGWPIVAN PAGIELLEIK PGSPTRPLPG
WDIRVLDTDG RPAPAGEDGA IVAKLPLPPG AFPTLWNDDE RFVKSYLSAF DGYYLTGDGG
RIDADGYVFV MGRTDDVINV AGHRLSTGGM EEVLASHPDV AECAVIGVSD QMKGQLPRGF
VVLKAGVLDR EGAATEGYED RLRAALVQMV RDQVGAVASL KEISIVPALP KTRSGKILRK
TMRGIADGID EPVPSTLDDA SVLDALRPIL RPR
//
