ID   D3CWU8_9ACTN            Unreviewed;       692 AA.
AC   D3CWU8;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Signal peptide peptidase SppA, 36K type {ECO:0000313|EMBL:EFC84836.1};
GN   ORFNames=FrEUN1fDRAFT_2018 {ECO:0000313|EMBL:EFC84836.1};
OS   Parafrankia sp. EUN1f.
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC   Parafrankia.
OX   NCBI_TaxID=102897 {ECO:0000313|EMBL:EFC84836.1, ECO:0000313|Proteomes:UP000004777};
RN   [1] {ECO:0000313|EMBL:EFC84836.1, ECO:0000313|Proteomes:UP000004777}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EUN1f {ECO:0000313|EMBL:EFC84836.1,
RC   ECO:0000313|Proteomes:UP000004777};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Tice H., Bruce D., Goodwin L.,
RA   Pitluck S., Larimer F., Land M.L., Hauser L., Beauchemin N., Sen A.,
RA   Fernandez M., Tisa L.;
RT   "The draft genome of Frankia sp. EUN1f.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S49 family.
CC       {ECO:0000256|ARBA:ARBA00008683}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFC84836.1}.
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DR   EMBL; ADGX01000024; EFC84836.1; -; Genomic_DNA.
DR   AlphaFoldDB; D3CWU8; -.
DR   MEROPS; S49.A08; -.
DR   Proteomes; UP000004777; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd07018; S49_SppA_67K_type; 1.
DR   CDD; cd07023; S49_Sppa_N_C; 1.
DR   Gene3D; 6.20.330.10; -; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR004635; Pept_S49_SppA.
DR   InterPro; IPR002142; Peptidase_S49.
DR   InterPro; IPR047217; S49_SppA_67K_type_N.
DR   InterPro; IPR047272; S49_SppA_C.
DR   NCBIfam; TIGR00706; SppA_dom; 1.
DR   PANTHER; PTHR33209; PROTEASE 4; 1.
DR   PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR   Pfam; PF01343; Peptidase_S49; 2.
DR   SUPFAM; SSF52096; ClpP/crotonase; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT   DOMAIN          110..241
FT                   /note="Peptidase S49"
FT                   /evidence="ECO:0000259|Pfam:PF01343"
FT   DOMAIN          426..571
FT                   /note="Peptidase S49"
FT                   /evidence="ECO:0000259|Pfam:PF01343"
FT   REGION          297..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   692 AA;  71578 MW;  EA75CBA513950138 CRC64;
     MADIQRFARR RAAPIILELD LTSDLVEGVP ADPLTAAVAH RRPTLREVVD GLRRAARDDR
     AKVLVAHIAA GGMPLARVQE VRDAVAEFRA SGGVTFAYAD TFGEFGGGTV AYYLACAFDE
     IWLAPPGDVG LTGVAMETPF LREALDRLGV SVEIGQRHEY KNAVNTLVER DFTPAHREAL
     GRIVDSCAEQ VVAEVSARRG LSPDQVRRMI DDAPMSGRAA LEAGLVDRIG YRDEAYDQVR
     TRARELAGTS GVGSDADGDG GVEPTLMYVW AYRRAEVRRE ASPVRRARGL AAALPASVLP
     GQSGGDRARW RSGTGPAAAT PDVAAEKAAA TPDGGAGTAA GGDPNVVPPE IDPRTSVVAL
     IHGTGPVVLG SAALPFGGPV LAADAVTAAF RAAARDSSVA AAVFRVDSPG GSYVASDVVR
     REIERFRATG RPVIVSMGAV AASGGYFVAL GGDLIVANPG TLTGSIGVFG GKQVVRDLLD
     KVGIGFGAVA AGENALMMSP RQSFTEAERA KLEEFLDRVY ADFVGKVAQA RRMSHAEAHE
     LARGRVWTGA DAHRHGLVDE LGGLAHAIDL AWARAGLPAE ETPRVRLTPK PSVLDRLRTP
     KSSEEPGAAA ARTVTSLGVP GIRGVLGVLT AFDALGGLGA LAGLGAVGGA HGGLPVGSDG
     FAGGWGALAP LAARAGLPVH GPLLMPPVGL VR
//