ID D3D3D2_9ACTN Unreviewed; 581 AA.
AC D3D3D2;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Superfamily I DNA and RNA helicase-like protein {ECO:0000313|EMBL:EFC82579.1};
GN ORFNames=FrEUN1fDRAFT_4302 {ECO:0000313|EMBL:EFC82579.1};
OS Parafrankia sp. EUN1f.
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC Parafrankia.
OX NCBI_TaxID=102897 {ECO:0000313|EMBL:EFC82579.1, ECO:0000313|Proteomes:UP000004777};
RN [1] {ECO:0000313|EMBL:EFC82579.1, ECO:0000313|Proteomes:UP000004777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EUN1f {ECO:0000313|EMBL:EFC82579.1,
RC ECO:0000313|Proteomes:UP000004777};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Tice H., Bruce D., Goodwin L.,
RA Pitluck S., Larimer F., Land M.L., Hauser L., Beauchemin N., Sen A.,
RA Fernandez M., Tisa L.;
RT "The draft genome of Frankia sp. EUN1f.";
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFC82579.1}.
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DR EMBL; ADGX01000070; EFC82579.1; -; Genomic_DNA.
DR RefSeq; WP_006542156.1; NZ_ADGX01000070.1.
DR AlphaFoldDB; D3D3D2; -.
DR Proteomes; UP000004777; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 7..289
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 28..35
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 581 AA; 63505 MW; 07D59226802CBF80 CRC64;
MAPPPNGLIY SPDQLALIEK PGSRMVRACP GAGKTQSIVE RFIRRPGLEG DRLGVALISF
TNAAITAVHE RCQDYPQLLR APNFVGTIDG FINRYIVGPI YTARRGHPPS FRDTWETTPG
RVYTSTVKAG LRLRLAWFSF AADGEATLVR RRIPGELRPQ TMSAVKDVMD GITAEARYKW
RSLTRAGFVD CEYARHLMTG YLVDPVLAGR LQRRFAHRFG EVIIDEFQDS NDGDVALIRF
LEASGISVVM VGDVDQEIYG FRQTAPGETG ALAGLVEAGE PLDGNYRSTP AICKVVDSLR
YGDSADTPCG PYKDEPRPVY VLKITGPAGA AKKITALAAR EGFAAEQIVV LSHGGSDARR
YAGAGKPLGS ATTTIERLAQ ATAIIRDGNG KPQDRARAMA LFESILRESA GGFADLHDND
FFEACRITQR QFRAGALRLA WRVSPYEATP QEFRDAIKSG IAELGWDKRF PDIAKKLRVT
KDQKWKHIPA AGNPDALAYS TVHGYKGLQS PAVALVIPKA RDGGIQEGVS NWDCGARHET
RRVLYVGASR AEQLLVLVVH DSQHAAVTTI LTRDGVLYEE A
//
