ID D3DI61_HYDTT Unreviewed; 237 AA.
AC D3DI61;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Diguanylate cyclase (GGDEF domain) {ECO:0000313|EMBL:BAI69513.1};
GN OrderedLocusNames=HTH_1055 {ECO:0000313|EMBL:BAI69513.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI69513.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI69513.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
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DR EMBL; AP011112; BAI69513.1; -; Genomic_DNA.
DR RefSeq; WP_012963693.1; NC_017161.1.
DR AlphaFoldDB; D3DI61; -.
DR STRING; 608538.HTH_1055; -.
DR KEGG; hth:HTH_1055; -.
DR eggNOG; COG2199; Bacteria.
DR OrthoDB; 9783388at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF4; TWO-COMPONENT RESPONSE REGULATOR; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..237
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 237 AA; 27083 MW; B93871DA557E689B CRC64;
MTYDQYLALG FGVLFASFAL GFKSSIAKKL SAIFSVSFLL QAVVGFFNQK PISILLLFYS
YLLISVAFFY GLSITRTVRA LANKAYTDQL TKVNNRTFLE DILKKELRHY ETLGINYCVV
FIDMFNFKKV NDAYGHTVGD RVLAEVGQRL RKSVRSDDFV VRYGGDEFLV VLKDVKEDRI
NSVIERLRES LNFDAEGIQV RANIGYAIYP KDGKSFEELV KVSIGRMYED KKAMENE
//
