ID D3DJY3_HYDTT Unreviewed; 382 AA.
AC D3DJY3;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Sensor histidine kinase {ECO:0000313|EMBL:BAI70135.1};
GN OrderedLocusNames=HTH_1688 {ECO:0000313|EMBL:BAI70135.1};
OS Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC Hydrogenobacter.
OX NCBI_TaxID=608538 {ECO:0000313|EMBL:BAI70135.1, ECO:0000313|Proteomes:UP000002574};
RN [1] {ECO:0000313|EMBL:BAI70135.1, ECO:0000313|Proteomes:UP000002574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6534 / IAM 12695 / TK-6 [Tokyo]
RC {ECO:0000313|Proteomes:UP000002574};
RX PubMed=20348262; DOI=10.1128/JB.00158-10;
RA Arai H., Kanbe H., Ishii M., Igarashi Y.;
RT "Complete genome sequence of the thermophilic, obligately
RT chemolithoautotrophic hydrogen-oxidizing bacterium Hydrogenobacter
RT thermophilus TK-6.";
RL J. Bacteriol. 192:2651-2652(2010).
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DR EMBL; AP011112; BAI70135.1; -; Genomic_DNA.
DR RefSeq; WP_012964315.1; NC_017161.1.
DR AlphaFoldDB; D3DJY3; -.
DR STRING; 608538.HTH_1688; -.
DR KEGG; hth:HTH_1688; -.
DR eggNOG; COG0642; Bacteria.
DR OrthoDB; 14660at2; -.
DR Proteomes; UP000002574; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR45528; SENSOR HISTIDINE KINASE CPXA; 1.
DR PANTHER; PTHR45528:SF9; SENSOR HISTIDINE KINASE YRKQ; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:BAI70135.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002574};
KW Transferase {ECO:0000313|EMBL:BAI70135.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 190..380
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 382 AA; 44018 MW; 691C81A1FD363D8B CRC64;
MKSPQSLYKL FLLNFLKFLL PIGIFFAFTF FNFRSDIIDL ESEYLLRTGE KLVDFLSHDE
DLLDNQYLGN DYIILIMDRK GQLLSSNMKM KDIININTFK ELKTQLGNIQ DVGNYLIYVN
TFPCKTSICK AIVALPKSRI ERRINVLLLS SMFATFITSI LIAFLSVLDI RKYLHEYELY
SKELKKVALY LSHEIKTPLS IILMNAPYVQ ADNEIKNAIE RAIRRIIKLT KNLKVLSDMD
LKPHRLTLIN VKGLINELVE FYRPHLYSKH LSINVDGVPK AAVLSDYELL YTLFLNLLDN
AVKYAKENTE IQVMGELQDN KLRVSISNVA EGEKHLNMDD ESYGLGLTIV DEIAKRLAVN
LSFKRDVQLF IAVVEMQVAE GR
//
