ID D3E2I4_METRM Unreviewed; 212 AA.
AC D3E2I4;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Precorrin-8X methylmutase CbiC {ECO:0000313|EMBL:ADC46745.1};
GN Name=cbiC {ECO:0000313|EMBL:ADC46745.1};
GN OrderedLocusNames=mru_0894 {ECO:0000313|EMBL:ADC46745.1};
OS Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 /
OS OCM 146 / M1) (Methanobacterium ruminantium).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=634498 {ECO:0000313|EMBL:ADC46745.1, ECO:0000313|Proteomes:UP000008680};
RN [1] {ECO:0000313|EMBL:ADC46745.1, ECO:0000313|Proteomes:UP000008680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1
RC {ECO:0000313|Proteomes:UP000008680};
RX PubMed=20126622; DOI=10.1371/journal.pone.0008926;
RA Leahy S.C., Kelly W.J., Altermann E., Ronimus R.S., Yeoman C.J.,
RA Pacheco D.M., Li D., Kong Z., McTavish S., Sang C., Lambie S.C.,
RA Janssen P.H., Dey D., Attwood G.T.;
RT "The genome sequence of the rumen methanogen Methanobrevibacter ruminantium
RT reveals new possibilities for controlling ruminant methane emissions.";
RL PLoS ONE 5:E8926-E8926(2010).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP001719; ADC46745.1; -; Genomic_DNA.
DR RefSeq; WP_012955696.1; NC_013790.1.
DR AlphaFoldDB; D3E2I4; -.
DR STRING; 634498.mru_0894; -.
DR GeneID; 8770545; -.
DR KEGG; mru:mru_0894; -.
DR PATRIC; fig|634498.28.peg.895; -.
DR eggNOG; arCOG02247; Archaea.
DR HOGENOM; CLU_084703_1_1_2; -.
DR OrthoDB; 24491at2157; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000008680; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008680}.
FT DOMAIN 12..205
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 212 AA; 23422 MW; C58ADFECC5970AF5 CRC64;
MKIELEQVEP AEIENRSMEI IESELPHEID PKLAPIIKRA VHTAADFDYV DNLCFSEDVV
DKALEAIKNG ACIVTDTQMA KAGINKAELK KHGGDVFCFM SDDDVRDMAK KNHSTRARAS
MDKASQLDRP LIFAIGNAPT ALIRLYELIQ EGKLKPELII GVPVGFVNVV QSKELIMQCD
VPYIVARGRK GGSNVAAAIS NALLYILRDQ MK
//
