ID D3E4A0_METRM Unreviewed; 112 AA.
AC D3E4A0;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000256|HAMAP-Rule:MF_00814};
GN Name=nac {ECO:0000256|HAMAP-Rule:MF_00814};
GN OrderedLocusNames=mru_1511 {ECO:0000313|EMBL:ADC47361.1};
OS Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 /
OS OCM 146 / M1) (Methanobacterium ruminantium).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=634498 {ECO:0000313|EMBL:ADC47361.1, ECO:0000313|Proteomes:UP000008680};
RN [1] {ECO:0000313|EMBL:ADC47361.1, ECO:0000313|Proteomes:UP000008680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1
RC {ECO:0000313|Proteomes:UP000008680};
RX PubMed=20126622; DOI=10.1371/journal.pone.0008926;
RA Leahy S.C., Kelly W.J., Altermann E., Ronimus R.S., Yeoman C.J.,
RA Pacheco D.M., Li D., Kong Z., McTavish S., Sang C., Lambie S.C.,
RA Janssen P.H., Dey D., Attwood G.T.;
RT "The genome sequence of the rumen methanogen Methanobrevibacter ruminantium
RT reveals new possibilities for controlling ruminant methane emissions.";
RL PLoS ONE 5:E8926-E8926(2010).
CC -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC {ECO:0000256|HAMAP-Rule:MF_00814}.
CC -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC {ECO:0000256|HAMAP-Rule:MF_00814}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000256|HAMAP-
CC Rule:MF_00814}.
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DR EMBL; CP001719; ADC47361.1; -; Genomic_DNA.
DR AlphaFoldDB; D3E4A0; -.
DR STRING; 634498.mru_1511; -.
DR KEGG; mru:mru_1511; -.
DR PATRIC; fig|634498.28.peg.1515; -.
DR eggNOG; arCOG04061; Archaea.
DR HOGENOM; CLU_146475_1_0_2; -.
DR Proteomes; UP000008680; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd22054; NAC_NACA; 1.
DR CDD; cd14359; UBA_AeNAC; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.20.70.30; Nascent polypeptide-associated complex domain; 1.
DR HAMAP; MF_00814; NAC_arch; 1.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR005231; NAC_arc.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR NCBIfam; TIGR00264; archaeal-type nascent polypeptide-associated complex protein; 1.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927, ECO:0000256|HAMAP-
KW Rule:MF_00814}; Reference proteome {ECO:0000313|Proteomes:UP000008680};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00814};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00814}.
FT DOMAIN 3..71
FT /note="NAC-A/B"
FT /evidence="ECO:0000259|PROSITE:PS51151"
SQ SEQUENCE 112 AA; 12338 MW; 7BB4A06C741D8EBC CRC64;
MNPKQLKKME RQMKKMGMDM KSIDDVEEVI IRCADKEIII TNADVSAMNV MGQETYQVTG
TAVEVEREVE LVIPDEDIEM VASTAGVSVE AAEEALRECG GDLAEAIMKL SN
//
