ID D3E4H4_METRM Unreviewed; 291 AA.
AC D3E4H4;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN OrderedLocusNames=mru_0018 {ECO:0000313|EMBL:ADC45870.1};
OS Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 /
OS OCM 146 / M1) (Methanobacterium ruminantium).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=634498 {ECO:0000313|EMBL:ADC45870.1, ECO:0000313|Proteomes:UP000008680};
RN [1] {ECO:0000313|EMBL:ADC45870.1, ECO:0000313|Proteomes:UP000008680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1
RC {ECO:0000313|Proteomes:UP000008680};
RX PubMed=20126622; DOI=10.1371/journal.pone.0008926;
RA Leahy S.C., Kelly W.J., Altermann E., Ronimus R.S., Yeoman C.J.,
RA Pacheco D.M., Li D., Kong Z., McTavish S., Sang C., Lambie S.C.,
RA Janssen P.H., Dey D., Attwood G.T.;
RT "The genome sequence of the rumen methanogen Methanobrevibacter ruminantium
RT reveals new possibilities for controlling ruminant methane emissions.";
RL PLoS ONE 5:E8926-E8926(2010).
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DR EMBL; CP001719; ADC45870.1; -; Genomic_DNA.
DR RefSeq; WP_012954826.1; NC_013790.1.
DR AlphaFoldDB; D3E4H4; -.
DR STRING; 634498.mru_0018; -.
DR GeneID; 8769635; -.
DR KEGG; mru:mru_0018; -.
DR PATRIC; fig|634498.28.peg.19; -.
DR eggNOG; arCOG09612; Archaea.
DR HOGENOM; CLU_955155_0_0_2; -.
DR OrthoDB; 379802at2157; -.
DR Proteomes; UP000008680; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008680};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..130
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 291 AA; 33137 MW; B2C6AE26CF43AC58 CRC64;
MSHDVFICYD EEDKDCAEAI CRIFEENNIK TWIRSRDVSS KDAARNLTEA IRNSKCFVLV
YSKNGKNTNY IINETDIAFS KEIPIILFKL DETSIPKDLE FILISKKKIV AYPHSKRQLK
TLVKETSDIL DRPTDDIKLD SNSVKTIERS NPKRKENNIK KAIGAAALIA AVLILIYLFV
IVPTGQNITD SGVFSMDVTH VEVDELAKGN KYTIYGESYN LPSDSDRYFM NLQFFDDKDN
VVYEVNSTAD EFKSGIIWSG DINKGDIKHI GFKLTDMDNK ILSQEDYNLG L
//
