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Database: UniProt
Entry: D3F8B2_CONWI
LinkDB: D3F8B2_CONWI
Original site: D3F8B2_CONWI 
ID   D3F8B2_CONWI            Unreviewed;       511 AA.
AC   D3F8B2;
DT   23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   23-MAR-2010, sequence version 1.
DT   23-MAY-2018, entry version 45.
DE   SubName: Full=NAD(P) transhydrogenase, alpha subunit {ECO:0000313|EMBL:ADB48982.1};
GN   OrderedLocusNames=Cwoe_0547 {ECO:0000313|EMBL:ADB48982.1};
OS   Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 /
OS   ID131577).
OC   Bacteria; Actinobacteria; Thermoleophilia; Solirubrobacterales;
OC   Conexibacteraceae; Conexibacter.
OX   NCBI_TaxID=469383 {ECO:0000313|EMBL:ADB48982.1, ECO:0000313|Proteomes:UP000008229};
RN   [1] {ECO:0000313|Proteomes:UP000008229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14684 / JCM 11494 / NBRC 100937 / ID131577
RC   {ECO:0000313|Proteomes:UP000008229};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Pukall R., Steenblock K.,
RA   Schneider S., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Conexibacter woesei DSM 14684.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001854; ADB48982.1; -; Genomic_DNA.
DR   RefSeq; WP_012932035.1; NC_013739.1.
DR   ProteinModelPortal; D3F8B2; -.
DR   STRING; 469383.Cwoe_0547; -.
DR   EnsemblBacteria; ADB48982; ADB48982; Cwoe_0547.
DR   KEGG; cwo:Cwoe_0547; -.
DR   eggNOG; ENOG4108IIE; Bacteria.
DR   eggNOG; COG3288; LUCA.
DR   HOGENOM; HOG000022121; -.
DR   KO; K00324; -.
DR   OMA; VIGHVHH; -.
DR   OrthoDB; POG091H0397; -.
DR   BioCyc; CWOE469383:G1GH5-546-MONOMER; -.
DR   Proteomes; UP000008229; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008746; F:NAD(P)+ transhydrogenase activity; IEA:InterPro.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   InterPro; IPR007886; AlaDH/PNT_N.
DR   InterPro; IPR007698; AlaDH/PNT_NAD(H)-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR026255; NADP_transhyd_a.
DR   InterPro; IPR024605; NADP_transhyd_a_C.
DR   Pfam; PF01262; AlaDh_PNT_C; 1.
DR   Pfam; PF05222; AlaDh_PNT_N; 1.
DR   Pfam; PF12769; PNTB_4TM; 1.
DR   PIRSF; PIRSF000203; NADP_transhydrogenase_alpha; 1.
DR   SMART; SM01002; AlaDh_PNT_C; 1.
DR   SMART; SM01003; AlaDh_PNT_N; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR00561; pntA; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008229};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008229};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    399    419       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    425    441       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    453    472       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    478    500       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        4    137       AlaDh_PNT_N. {ECO:0000259|SMART:SM01003}.
FT   DOMAIN      146    309       AlaDh_PNT_C. {ECO:0000259|SMART:SM01002}.
SQ   SEQUENCE   511 AA;  53233 MW;  2BE995931FB0D8FC CRC64;
     MLIGVPRETN AGETRVAATP ATLRQLVGLG YDVVVEAGAG VLSSFDDDAY ASAGAAVGSA
     EQAWQADVVF RVNGPTVDEI AKLKDGATIV ALLAPALRPE LVDALAQRPI TALAMDAVPR
     ISRAQSLDVL SSMANIAGYR AVIEAAHVFG RFFTGQVTAA GKVPPAKVLI AGAGVAGLAA
     IGAANSLGAI VRATDPRPEV ADQVRSLGGE FLSVMELEVS SDGYARATSD DYNRLAAELY
     TEQAKDVDII ITTALIPGRP APTLMTAEQV ALMRSGSVIV DMAASMGGNV EGSVAGKAIV
     TDNGVTIIGY TDLAGRLPAQ ASQLYGTNLV NLMKLLTPER DGQVRLDFDD VVQRSMTVVR
     DGERTWPPPP VQVSAAPAAR SESARAVEAA PAKAPRPAWV RYAPIAVGLL ALWAVNAFAP
     DPLPSHFTVL MLAVVVGYYV IGKVHHALHT PLMSVTNAIS GIIVVGAMLQ LGEQDDTVIR
     VLATVAILFA SINVFGGFAV TRRMLGMFNR G
//
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