ID D3IG04_9BACT Unreviewed; 638 AA.
AC D3IG04;
DT 23-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 23-MAR-2010, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=DNA-binding protein HU {ECO:0000313|EMBL:EFC68950.1};
GN Name=hup {ECO:0000313|EMBL:EFC68950.1};
GN ORFNames=HMPREF0670_00273 {ECO:0000313|EMBL:EFC68950.1};
OS Prevotella sp. oral taxon 317 str. F0108.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=575615 {ECO:0000313|EMBL:EFC68950.1, ECO:0000313|Proteomes:UP000003829};
RN [1] {ECO:0000313|EMBL:EFC68950.1, ECO:0000313|Proteomes:UP000003829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0108 {ECO:0000313|EMBL:EFC68950.1,
RC ECO:0000313|Proteomes:UP000003829};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Prevotella sp. Oral Taxon 317 strain F0108.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000256|RuleBase:RU003939}.
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DR EMBL; GG740072; EFC68950.1; -; Genomic_DNA.
DR AlphaFoldDB; D3IG04; -.
DR eggNOG; COG0776; Bacteria.
DR eggNOG; COG1388; Bacteria.
DR HOGENOM; CLU_029436_1_0_10; -.
DR Proteomes; UP000003829; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR Gene3D; 4.10.520.10; IHF-like DNA-binding proteins; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR PANTHER; PTHR33175; DNA-BINDING PROTEIN HU; 1.
DR PANTHER; PTHR33175:SF2; INTEGRATION HOST FACTOR SUBUNIT ALPHA; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; IHF-like DNA-binding proteins; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:EFC68950.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003829};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 124..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..303
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..414
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 638 AA; 70035 MW; 62C0DADA47283F15 CRC64;
MEVKMNNRVG IRELAMALVN KNKLSLKEAE NFVATMFDTL NVGLNDDKQV KLKGLGTFKV
MSVSARKSVD VNTGEPIIID GRDKISFTPD STMKDLVNKP FAQFDTVVIN DGVDLKELER
MDWTETTSDA DRTPLNDNSD DAELTPTSTL PPSKIETVVN QAADALASAP VEVPNETEVP
VKKAPEKSHI LTMQQLSALN GDQRPIAVAE NAVNATTQLT LTADQLRLLN GGERHNEQEQ
RVVQRAELEL EETSIETGTG APDILSDDET EGTQAQTQSV EGLSEQADET PDATEMDVVD
GVEASDVEET HNDVEGEPAK EEDMLDADND IVDTDTDADN ECEPVQAACA MPVVEGLTLV
DENLETEDEL TPEDTESNSA DDSDVETELQ SDEEDSDDDD ETDENSCEYE EDEWEEEERR
RKRRRLIVAC VVGIIVVVGG VAWYLLNQMQ LKDNRISHLE TLLNTSKPSD SKASEQPLSP
TDSAREDSIN RLIDAQTKAD LAASEAKIAQ NAEKKAEKAD NKKPAATASE NKKPAEKTAD
KPAPKQEKAK ANTTENQNYK QYEKDARVRT GAYKIVGIAH VVTVTKGQTL YSLSKSMLGP
GMECYIEAVN GNVKELKEGQ KIKIPKLELK KPKTTSKN
//
