ID D3PQX8_MEIRD Unreviewed; 348 AA.
AC D3PQX8;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Aminoglycoside phosphotransferase {ECO:0000313|EMBL:AGK04328.1};
GN OrderedLocusNames=Mrub_1097 {ECO:0000313|EMBL:ADD27861.1};
GN ORFNames=K649_05130 {ECO:0000313|EMBL:AGK04328.1};
OS Meiothermus ruber (strain ATCC 35948 / DSM 1279 / VKM B-1258 / 21) (Thermus
OS ruber).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Meiothermus.
OX NCBI_TaxID=504728 {ECO:0000313|EMBL:AGK04328.1, ECO:0000313|Proteomes:UP000013026};
RN [1] {ECO:0000313|EMBL:ADD27861.1, ECO:0000313|Proteomes:UP000006655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35948 / DSM 1279 / VKM B-1258 / 21
RC {ECO:0000313|Proteomes:UP000006655}, and DSM 1279
RC {ECO:0000313|EMBL:ADD27861.1};
RX PubMed=21304689; DOI=10.4056/sigs.1032748;
RA Tindall B.J., Sikorski J., Lucas S., Goltsman E., Copeland A.,
RA Glavina Del Rio T., Nolan M., Tice H., Cheng J.F., Han C., Pitluck S.,
RA Liolios K., Ivanova N., Mavromatis K., Ovchinnikova G., Pati A.,
RA Fahnrich R., Goodwin L., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Lapidus A.;
RT "Complete genome sequence of Meiothermus ruber type strain (21).";
RL Stand. Genomic Sci. 3:26-36(2010).
RN [2] {ECO:0000313|EMBL:AGK04328.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 1279 {ECO:0000313|EMBL:AGK04328.1};
RA Klammer A., Drake J., Heiner C., Clum A., Copeland A., Huddleston J.,
RA Eichler E., Turner S.W.;
RT "Non-Hybrid, Finished Microbial Genome Assemblies from Long-Read SMRT
RT Sequencing Data.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AGK04328.1, ECO:0000313|Proteomes:UP000013026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35948 / DSM 1279 / VKM B-1258 / 21
RC {ECO:0000313|Proteomes:UP000013026}, and DSM 1279
RC {ECO:0000313|EMBL:AGK04328.1};
RA Chin J., Alexander D.H., Marks P., Korlach J., Clum A., Copeland A.;
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001743; ADD27861.1; -; Genomic_DNA.
DR EMBL; CP005385; AGK04328.1; -; Genomic_DNA.
DR RefSeq; WP_013013380.1; NC_021081.1.
DR AlphaFoldDB; D3PQX8; -.
DR STRING; 504728.K649_05130; -.
DR KEGG; mrb:Mrub_1097; -.
DR KEGG; mre:K649_05130; -.
DR PATRIC; fig|504728.9.peg.1058; -.
DR eggNOG; COG3173; Bacteria.
DR OrthoDB; 3806873at2; -.
DR Proteomes; UP000006655; Chromosome.
DR Proteomes; UP000013026; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd05154; ACAD10_11_N-like; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR041726; ACAD10_11_N.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR47829:SF1; AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR47829; HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:AGK04328.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..269
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 348 AA; 39276 MW; E21F6DCF53C32F70 CRC64;
MTDQLAPIRP GEELDIARLQ AYLLEHLPGA EGRLEVLQFP SGFSNLTYLL RLGGQELVLR
RPPFGANIKT AHDMAREYRI LSALKPVYPK VPRPLLYCPD DSVIGAPFYL MERLHGVILR
TQPPPDLTPE RMRKICEAAL EALVELHSLD YQKAGLGDLG RPEGYVERQV RGWTERYQKA
RTEAVPGMEQ AMEWLAAHIP PGSSAALIHN DFKYDNLLLN PADLTQVMAV LDWEMATLGD
PLMDLGTTLG YWAEPDDPPG LRRFGLTHLP GNLRRAELVA AYAARSGRNV DNIVFYYVFG
LFKVGVIMQQ IFFRYQKGYT RDQRFAVLIH LIREIGQKIQ KAIATGEV
//
