ID D3PZM1_STANL Unreviewed; 407 AA.
AC D3PZM1;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=4-hydroxy-3-methylbut-2-enyl diphosphate reductase {ECO:0000313|EMBL:ADD41695.1};
DE EC=1.17.1.2 {ECO:0000313|EMBL:ADD41695.1};
GN OrderedLocusNames=Snas_1999 {ECO:0000313|EMBL:ADD41695.1};
OS Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 /
OS NBRC 102104 / LLR-40K-21).
OC Bacteria; Actinomycetota; Actinomycetes; Glycomycetales; Glycomycetaceae;
OC Stackebrandtia.
OX NCBI_TaxID=446470 {ECO:0000313|EMBL:ADD41695.1, ECO:0000313|Proteomes:UP000000844};
RN [1] {ECO:0000313|EMBL:ADD41695.1, ECO:0000313|Proteomes:UP000000844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 /
RC LLR-40K-21 {ECO:0000313|Proteomes:UP000000844};
RX PubMed=21304662; DOI=10.4056/sigs.47643;
RA Munk C., Lapidus A., Copeland A., Jando M., Mayilraj S.,
RA Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F.,
RA Han C., Detter J.C., Bruce D., Goodwin L., Chain P., Pitluck S., Goker M.,
RA Ovchinikova G., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-
RT 40K-21).";
RL Stand. Genomic Sci. 1:292-299(2009).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP001778; ADD41695.1; -; Genomic_DNA.
DR RefSeq; WP_013017266.1; NC_013947.1.
DR AlphaFoldDB; D3PZM1; -.
DR STRING; 446470.Snas_1999; -.
DR KEGG; sna:Snas_1999; -.
DR eggNOG; COG0761; Bacteria.
DR HOGENOM; CLU_027486_3_1_11; -.
DR OrthoDB; 3627470at2; -.
DR Proteomes; UP000000844; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051745; F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:InterPro.
DR Gene3D; 3.40.50.11270; -; 1.
DR Gene3D; 3.40.1010.20; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain; 2.
DR InterPro; IPR003451; LytB/IspH.
DR PANTHER; PTHR30426; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR30426:SF0; 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF02401; LYTB; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:ADD41695.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000844}.
SQ SEQUENCE 407 AA; 42932 MW; E4F5111FCD92EBB6 CRC64;
MGRSIWVEWF TTSGVSTGEV VVLEEFRHPR RGRVRSPARA LIAAWLRRRG LRVRRGKLPL
YGDGAQGDSA LLCVSYLDET HGAAGFAVAV PGEDAGLRAM VESMVMAWVS VLRTRRVLLA
GGEPWCVGGR RVVELVESTL DDGAELVHVV GDLAASPERR VALRERGVVP VTALDEVPDG
ARVVVGAAGI PEEQRVKAAK RGVRIVDGTC PHIASGKAQV RRYAERGDAV VLVGQRGHAS
TEALSGQAPD ATLVVETTAD VEQMRGGDGV SAVPVPSMAI GAVVPMLAAL RRRFPKLPVQ
HPDQWCYQTQ DRLATVRELA GTADVVFVLG PPESPETVRL LDVAASNAVA VGGLGDIEPS
YLVDVGSVGV VVGGDASEGL RGELLTALGG LGPVAVSELR VQTRTMD
//
