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Database: UniProt
Entry: D3Q4S8_STANL
LinkDB: D3Q4S8_STANL
Original site: D3Q4S8_STANL 
ID   D3Q4S8_STANL            Unreviewed;       332 AA.
AC   D3Q4S8;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU000716};
GN   OrderedLocusNames=Snas_2425 {ECO:0000313|EMBL:ADD42108.1};
OS   Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 /
OS   NBRC 102104 / LLR-40K-21).
OC   Bacteria; Actinomycetota; Actinomycetes; Glycomycetales; Glycomycetaceae;
OC   Stackebrandtia.
OX   NCBI_TaxID=446470 {ECO:0000313|EMBL:ADD42108.1, ECO:0000313|Proteomes:UP000000844};
RN   [1] {ECO:0000313|EMBL:ADD42108.1, ECO:0000313|Proteomes:UP000000844}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 /
RC   LLR-40K-21 {ECO:0000313|Proteomes:UP000000844};
RX   PubMed=21304662; DOI=10.4056/sigs.47643;
RA   Munk C., Lapidus A., Copeland A., Jando M., Mayilraj S.,
RA   Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F.,
RA   Han C., Detter J.C., Bruce D., Goodwin L., Chain P., Pitluck S., Goker M.,
RA   Ovchinikova G., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-
RT   40K-21).";
RL   Stand. Genomic Sci. 1:292-299(2009).
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC       formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC       omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC       transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641, ECO:0000256|RuleBase:RU000716}.
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DR   EMBL; CP001778; ADD42108.1; -; Genomic_DNA.
DR   RefSeq; WP_013017679.1; NC_013947.1.
DR   AlphaFoldDB; D3Q4S8; -.
DR   STRING; 446470.Snas_2425; -.
DR   KEGG; sna:Snas_2425; -.
DR   eggNOG; COG1595; Bacteria.
DR   HOGENOM; CLU_043648_0_0_11; -.
DR   OrthoDB; 3806887at2; -.
DR   Proteomes; UP000000844; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProt.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014305; RNA_pol_sigma-G_actinobac.
DR   InterPro; IPR000838; RNA_pol_sigma70_ECF_CS.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   NCBIfam; TIGR02960; SigX5; 1.
DR   PANTHER; PTHR43133:SF46; ECF RNA POLYMERASE SIGMA FACTOR SIGG; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR   PROSITE; PS01063; SIGMA70_ECF; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU000716};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000844};
KW   Sigma factor {ECO:0000256|RuleBase:RU000716};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU000716};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU000716}.
FT   DOMAIN          20..86
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          140..192
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
SQ   SEQUENCE   332 AA;  36137 MW;  62D8493065B8611A CRC64;
     MTTDPARAES GPGDAAHRLE PYRRELLAHC YRMVGSADEA EDLVQETFLR AWRSRRDFEG
     RSSWRTWLYR IATNVCLTAL EQRGRRALPS GLGAPAEDAT TPPRPAEPGI AWLQPIPDAQ
     VAPRSADPAT VVTAREGLRL ALIASLQYLP ARQRAVLLLR EVLAFPAAEV ASMLDTTTAA
     VKSALQRARA RLDDVDPKGE PLREPTEPRT RELLEQYITG FENADTAALE RALRADAAIE
     LVGTRTWFSG RATCLGYLRT VIGRCGDWRM LPTAANGQPA VAAYVRSADG IHRAFGIGVL
     TVSQEGISHV HVFGGGADLT ATFGLPPVWP GR
//
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