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Database: UniProt
Entry: D3Q5B4_STANL
LinkDB: D3Q5B4_STANL
Original site: D3Q5B4_STANL 
ID   D3Q5B4_STANL            Unreviewed;       347 AA.
AC   D3Q5B4;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   16-OCT-2019, entry version 58.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   OrderedLocusNames=Snas_4518 {ECO:0000313|EMBL:ADD44163.1};
OS   Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC
OS   102104 / LLR-40K-21).
OC   Bacteria; Actinobacteria; Glycomycetales; Glycomycetaceae;
OC   Stackebrandtia.
OX   NCBI_TaxID=446470 {ECO:0000313|EMBL:ADD44163.1, ECO:0000313|Proteomes:UP000000844};
RN   [1] {ECO:0000313|EMBL:ADD44163.1, ECO:0000313|Proteomes:UP000000844}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21
RC   {ECO:0000313|Proteomes:UP000000844};
RX   PubMed=21304662; DOI=10.4056/sigs.47643;
RA   Munk C., Lapidus A., Copeland A., Jando M., Mayilraj S.,
RA   Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H., Cheng J.F.,
RA   Han C., Detter J.C., Bruce D., Goodwin L., Chain P., Pitluck S.,
RA   Goker M., Ovchinikova G., Pati A., Ivanova N., Mavromatis K., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA   Klenk H.P.;
RT   "Complete genome sequence of Stackebrandtia nassauensis type strain
RT   (LLR-40K-21).";
RL   Stand. Genomic Sci. 1:292-299(2009).
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CP001778; ADD44163.1; -; Genomic_DNA.
DR   RefSeq; WP_013019734.1; NC_013947.1.
DR   STRING; 446470.Snas_4518; -.
DR   EnsemblBacteria; ADD44163; ADD44163; Snas_4518.
DR   KEGG; sna:Snas_4518; -.
DR   eggNOG; ENOG4105E99; Bacteria.
DR   eggNOG; COG0722; LUCA.
DR   HOGENOM; HOG000220501; -.
DR   OMA; ISDLICW; -.
DR   OrthoDB; 853329at2; -.
DR   BioCyc; SNAS446470:G1GG8-4508-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000000844; Chromosome.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000844};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000844};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:ADD44163.1}.
FT   DOMAIN       32    323       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   347 AA;  36558 MW;  65AC7463C85C9DAD CRC64;
     MSVLSGPASL RATVTTDPKL AAEVELSRGT IRAILDGADQ RLLILVGPCS VHDPRELRRY
     ATGLAEVAAA HAEDVYLVVR AYTEKPRTRH GWPGLLLDPG LDGGYAVPAG LAETRRVLTE
     INTLGLPVAC EFVEPQLAPY LSDLVSWAGI GARTVESPPH RRLASHLPMP VGFKNRVDGA
     ITPAVDAIAV ASRPQPVITV DDHGRCAWTV SDGNPDTHLV LRGGETGTNY AAHQVNHALG
     LLADVQSHPK LIVDCSHGNS GKDHNRQPVV AEAIAAQIAA GQTGIAGVML ESYLSPGAQS
     LDGTLRPGVS VTDACLGFAD TAEVIENLAL AAKQRRAGRT TELVNVR
//
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