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Database: UniProt
Entry: D3S1B1_FERPA
LinkDB: D3S1B1_FERPA
Original site: D3S1B1_FERPA 
ID   D3S1B1_FERPA            Unreviewed;       637 AA.
AC   D3S1B1;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 47.
DE   SubName: Full=Prephenate dehydratase {ECO:0000313|EMBL:ADC66375.1};
GN   OrderedLocusNames=Ferp_2251 {ECO:0000313|EMBL:ADC66375.1};
OS   Ferroglobus placidus (strain DSM 10642 / AEDII12DO).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales;
OC   Archaeoglobaceae; Ferroglobus.
OX   NCBI_TaxID=589924 {ECO:0000313|EMBL:ADC66375.1, ECO:0000313|Proteomes:UP000002613};
RN   [1] {ECO:0000313|Proteomes:UP000002613}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10642 / AEDII12DO {ECO:0000313|Proteomes:UP000002613};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Tapia R.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Holmes D.,
RA   Lovley D., Kyrpides N., Anderson I.J., Woyke T.;
RT   "Complete sequence of Ferroglobus placidus DSM 10642.";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADC66375.1, ECO:0000313|Proteomes:UP000002613}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10642 / AEDII12DO {ECO:0000313|Proteomes:UP000002613};
RX   PubMed=22180810; DOI=10.4056/sigs.2225018;
RA   Anderson I., Risso C., Holmes D., Lucas S., Copeland A., Lapidus A.,
RA   Cheng J.F., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T.,
RA   Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L.,
RA   Woyke T., Lovley D., Kyrpides N., Ivanova N.;
RT   "Complete genome sequence of Ferroglobus placidus AEDII12DO.";
RL   Stand. Genomic Sci. 5:50-60(2011).
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DR   EMBL; CP001899; ADC66375.1; -; Genomic_DNA.
DR   RefSeq; WP_012966713.1; NC_013849.1.
DR   STRING; 589924.Ferp_2251; -.
DR   EnsemblBacteria; ADC66375; ADC66375; Ferp_2251.
DR   GeneID; 8779790; -.
DR   KEGG; fpl:Ferp_2251; -.
DR   eggNOG; ENOG4102T9Y; Archaea.
DR   eggNOG; COG0077; LUCA.
DR   eggNOG; COG0287; LUCA.
DR   eggNOG; COG1605; LUCA.
DR   HOGENOM; HOG000279363; -.
DR   KO; K14170; -.
DR   OMA; CMGFINN; -.
DR   OrthoDB; 23090at2157; -.
DR   BioCyc; FPLA589924:G1GHF-2262-MONOMER; -.
DR   Proteomes; UP000002613; Chromosome.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046417; P:chorismate metabolic process; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.20.59.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR036263; Chorismate_II_sf.
DR   InterPro; IPR036979; CM_dom_sf.
DR   InterPro; IPR002701; CM_II_prokaryot.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR003099; Prephen_DH.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF01817; CM_2; 1.
DR   Pfam; PF02153; PDH; 1.
DR   Pfam; PF00800; PDT; 1.
DR   SMART; SM00830; CM_2; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF48600; SSF48600; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS51168; CHORISMATE_MUT_2; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002613};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002613}.
FT   DOMAIN        1    262       Prephenate/arogenate dehydrogenase.
FT                                {ECO:0000259|PROSITE:PS51176}.
FT   DOMAIN      260    348       Chorismate mutase. {ECO:0000259|PROSITE:
FT                                PS51168}.
FT   DOMAIN      353    527       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      538    611       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   COILED      580    600       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   637 AA;  72561 MW;  3E4EDBFC15FE6A52 CRC64;
     MKICIYGMGG MGSFFKNFFE NRGYFVKGYD VVKEKSEIRL EEVKNFDVIF LCVPMDKIED
     AVSEIKETAD KNALLVDIAS VKKPFVKIYE SSGFEWMSIH PMFGPDSEIG LSNVIVVRLP
     KDERAVRIVE EFRKSGAIVS FLSLEEHDEE MAKIQSTSHF LLLTLSYYLR EWFNEEKLKI
     LSPISLTLIK LASRIINQDW KMYEYILENG REVRKEIIKA ASEVDRFIEE GKVQELFDYL
     RGAFKNGKNT TIILDSARTT LTPNSLEELR GYIKTVDSLI LRLIEKRVDA GRRIALEKMK
     RNEPIEVSEV EYFKLKELTS KTSLDAGSVS SIFEEIMSLT KAEEYKVAGV EKKVAVLGPA
     GSFSEEAALK LIDSKLPLIY CSSVEEIVKA VESGKADFGI LPIENSINGT VIPSLDALLK
     HDVEVFAETE VEVNLNLAAK KLIDLKDVEV IYSHPQAVSQ CMTFINNYLP HAEIRYTRST
     SDAVSLLDEK SAAIVSENAA KIYRLQILRR SIQDAKENVT RFYVVRRRGG EVRGNVTALF
     FGVEDKPGAL FSVLEIFKRR NINLRKLESR PSGIKLGDYI FFVEAEKKLE EEELKELKER
     TTFYKVVGVF EKIDRLNVFI SERKESSSSE DRRAKEA
//
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