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Database: UniProt
Entry: D3SNX5_THEAH
LinkDB: D3SNX5_THEAH
Original site: D3SNX5_THEAH 
ID   D3SNX5_THEAH            Unreviewed;       643 AA.
AC   D3SNX5;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 58.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=Thal_0227 {ECO:0000313|EMBL:ADC88862.1};
OS   Thermocrinis albus (strain DSM 14484 / JCM 11386 / HI 11/12).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Thermocrinis.
OX   NCBI_TaxID=638303 {ECO:0000313|EMBL:ADC88862.1, ECO:0000313|Proteomes:UP000002043};
RN   [1] {ECO:0000313|Proteomes:UP000002043}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14484 / JCM 11386 / HI 11/12
RC   {ECO:0000313|Proteomes:UP000002043};
RX   DOI=10.4056/sigs.761490;
RA   Wirth R., Sikorski J., Brambilla E., Misra M., Lapidus A.,
RA   Copeland A., Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Han C.,
RA   Detter J.C., Tapia R., Bruce D., Goodwin L., Pitluck S., Pati A.,
RA   Anderson I., Ivanova N., Mavromatis K., Mikhailova N., Chen A.,
RA   Palaniappan K., Bilek Y., Hader T., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Tindall B.J., Rohde M., Goker M., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Thermocrinis albus type strain (HI
RT   11/12T).";
RL   Stand. Genomic Sci. 2:194-202(2010).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP001931; ADC88862.1; -; Genomic_DNA.
DR   RefSeq; WP_012991269.1; NC_013894.1.
DR   STRING; 638303.Thal_0227; -.
DR   EnsemblBacteria; ADC88862; ADC88862; Thal_0227.
DR   KEGG; tal:Thal_0227; -.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   HOGENOM; HOG000054021; -.
DR   KO; K04759; -.
DR   OMA; MEMPDYE; -.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; TALB638303:G1GHJ-231-MONOMER; -.
DR   Proteomes; UP000002043; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002043};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002043};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    217    240       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    278    303       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    323    346       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    358    381       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    387    408       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    446    465       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    586    606       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    618    637       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        3    165       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   643 AA;  72066 MW;  61414CDBF8D27B56 CRC64;
     MKKVLVALVG NPNVGKTSLL NHIAGTTLRV GNWPGVTVEK REGKIFYGDY EITFVDLPGI
     YTLEPVSEDE QIAYHFLKEE KVDLIINVIE APNMERDLFL TAQLMELGKP MVIALNMWDE
     ALRLGIDIDT SRMQELLGLP VVKTNGRKGE GVKDLLEAVV RAIESDLRPF PLPYLRTPLQ
     DQELRDRRLG FAHGLYTEVV KRRSTVSQDI TEALDRIVLH PVMGPVFFVF VMFLLFKVAF
     DVSSPFMDWL DGFFQNFLGP LVKRYVGNGF WGSFLSEAVV GGVGFVLTFV PLIASLFFLL
     SFLEFSGYIP RVAFLTDRFM HRIGLHGKGV IPLLLGFGCN VPAVLATRTL DTKRDKMLVL
     AMIPFMSCPA RLVVFSFFAT LFFPSPVLVM LGLYLMGVMT AIVTGFVLKK LVYTGSLTHF
     VMELPPYRLP TLKLLLRITW VHVKDFLYRA GTLILAVAVV VWSLLHLPVG VSKVEDSVAA
     HIGKVLLPIF EPMGIHDWRI TTSLIPAFMA REVVLGSMAT IYAVEEESRE LEDPWKALEE
     QGVALLSAFK EAGRNLLSPV PKVFEVKEEH SPLRQAVSRV MDPPTALAFM VFMLLYMSCL
     GTFSVLKREA GGRFALLFLA YSFLIAWMAG VGIYRLWSIL LSL
//
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