ID D3T1E2_NATMM Unreviewed; 372 AA.
AC D3T1E2;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Histone deacetylase {ECO:0000313|EMBL:ADD07401.1, ECO:0000313|EMBL:ELY32425.1};
GN Name=hda1c {ECO:0000313|EMBL:ADD07401.1};
GN OrderedLocusNames=Nmag_3860 {ECO:0000313|EMBL:ADD07401.1};
GN ORFNames=C500_04009 {ECO:0000313|EMBL:ELY32425.1};
OS Natrialba magadii (strain ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 /
OS IAM 13178 / JCM 8861 / NBRC 102185 / NCIMB 2190 / MS3) (Natronobacterium
OS magadii).
OG Plasmid pNMAG01 {ECO:0000313|EMBL:ADD07401.1,
OG ECO:0000313|Proteomes:UP000001879}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrialba.
OX NCBI_TaxID=547559 {ECO:0000313|EMBL:ADD07401.1, ECO:0000313|Proteomes:UP000001879};
RN [1] {ECO:0000313|Proteomes:UP000001879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM
RC 8861 / NBRC 102185 / NCIMB 2190 / MS3
RC {ECO:0000313|Proteomes:UP000001879};
RC PLASMID=pNMAG01 {ECO:0000313|Proteomes:UP000001879};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Saunders E., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., De Castro R.E.,
RA Maupin-Furlow J.A., Woyke T.;
RT "Complete sequence of plasmid 1 of Natrialba magadii ATCC 43099.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADD07401.1, ECO:0000313|Proteomes:UP000001879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43099 {ECO:0000313|EMBL:ADD07401.1}, and ATCC 43099 / DSM
RC 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM 8861 / NBRC 102185 /
RC NCIMB 2190 / MS3 {ECO:0000313|Proteomes:UP000001879};
RX PubMed=22559199; DOI=10.1186/1471-2164-13-165;
RA Siddaramappa S., Challacombe J.F., Decastro R.E., Pfeiffer F., Sastre D.E.,
RA Gimenez M.I., Paggi R.A., Detter J.C., Davenport K.W., Goodwin L.A.,
RA Kyrpides N., Tapia R., Pitluck S., Lucas S., Woyke T., Maupin-Furlow J.A.;
RT "A comparative genomics perspective on the genetic content of the
RT alkaliphilic haloarchaeon Natrialba magadii ATCC 43099T.";
RL BMC Genomics 13:165-165(2012).
RN [3] {ECO:0000313|EMBL:ELY32425.1, ECO:0000313|Proteomes:UP000011543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM
RC 8861 / NBRC 102185 / NCIMB 2190 / MS3
RC {ECO:0000313|Proteomes:UP000011543}, and MS-3
RC {ECO:0000313|EMBL:ELY32425.1};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [4] {ECO:0000313|EMBL:ADD07401.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43099 {ECO:0000313|EMBL:ADD07401.1};
RC PLASMID=pNMAG01 {ECO:0000313|EMBL:ADD07401.1};
RA Pfeiffer F.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001933; ADD07401.1; -; Genomic_DNA.
DR EMBL; AOHS01000016; ELY32425.1; -; Genomic_DNA.
DR RefSeq; WP_004214372.1; NZ_AOHS01000016.1.
DR AlphaFoldDB; D3T1E2; -.
DR GeneID; 8826730; -.
DR KEGG; nmg:Nmag_3860; -.
DR PATRIC; fig|547559.17.peg.764; -.
DR HOGENOM; CLU_007727_8_2_2; -.
DR OrthoDB; 147549at2157; -.
DR Proteomes; UP000001879; Plasmid pNMAG01.
DR Proteomes; UP000011543; Unassembled WGS sequence.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:InterPro.
DR CDD; cd09996; HDAC_classII_1; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR003084; His_deacetylse_1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF9; HISTONE DEACETYLASE 8; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR PRINTS; PR01271; HISDACETLASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:ADD07401.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001879}.
FT DOMAIN 37..330
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 372 AA; 40903 MW; FAE0B8128FF64B9C CRC64;
MGRTITAFWD ESFIAHEQPA GEFESEWTGR LAYRQPHPDR PERLKNIYSI LQAELADHVT
LADVEPATRV QLERTHTADH IDDLQAFCAD GGGRITAETG ANEHTFRAAT HAAGAACLAA
EHALEHSLDN VPYAMVRPSG HHAQPEQVDG FCYFNNVAVA ADHILETTDT ERVAIVDWDV
HHGNGTQECF EDRDDVLVIG IHNDHWSWDP EAHPQTGDLD EVGTGDGEGY NVNVPLPPGT
GDEGYEHVFD RIVEPLLRSY DPDLLLISAG QDAGTMDPLG RNVVTKGGFE ELGRRARVLA
DEYAGGNLAV VQEGGYQVSH LAYATLGVLE GVLGVETGID DPMAWMDEDY DSARRTIEDI
ATYHSEYWPA LE
//
