ID D3UFR5_HELM1 Unreviewed; 730 AA.
AC D3UFR5;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Iron-regulated outer membrane protein FrpB1 {ECO:0000313|EMBL:CBG39336.1};
GN Name=FrpB1 {ECO:0000313|EMBL:CBG39336.1};
GN OrderedLocusNames=HMU00720 {ECO:0000313|EMBL:CBG39336.1};
OS Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198)
OS (Campylobacter mustelae).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=679897 {ECO:0000313|EMBL:CBG39336.1, ECO:0000313|Proteomes:UP000001522};
RN [1] {ECO:0000313|EMBL:CBG39336.1, ECO:0000313|Proteomes:UP000001522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43772 / LMG 18044 / NCTC 12198 / 12198
RC {ECO:0000313|Proteomes:UP000001522};
RX PubMed=20219135; DOI=10.1186/1471-2164-11-164;
RA O'Toole P.W., Snelling W.J., Canchaya C., Forde B.M., Hardie K.R.,
RA Josenhans C., Graham R.L.J., McMullan G., Parkhill J., Belda E.,
RA Bentley S.D.;
RT "Comparative genomics and proteomics of Helicobacter mustelae, an
RT ulcerogenic and carcinogenic gastric pathogen.";
RL BMC Genomics 11:164-164(2010).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004571}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004571}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC {ECO:0000256|ARBA:ARBA00009810, ECO:0000256|RuleBase:RU003357}.
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DR EMBL; FN555004; CBG39336.1; -; Genomic_DNA.
DR RefSeq; WP_013022434.1; NC_013949.1.
DR AlphaFoldDB; D3UFR5; -.
DR STRING; 679897.HMU00720; -.
DR KEGG; hms:HMU00720; -.
DR eggNOG; COG1629; Bacteria.
DR HOGENOM; CLU_008287_19_2_7; -.
DR Proteomes; UP000001522; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.40.170.20; TonB-dependent receptor, beta-barrel domain; 1.
DR Gene3D; 2.170.130.10; TonB-dependent receptor, plug domain; 1.
DR InterPro; IPR012910; Plug_dom.
DR InterPro; IPR037066; Plug_dom_sf.
DR InterPro; IPR039426; TonB-dep_rcpt-like.
DR InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR PANTHER; PTHR30069:SF41; TONB-DEPENDENT HEME RECEPTOR A; 1.
DR PANTHER; PTHR30069; TONB-DEPENDENT OUTER MEMBRANE RECEPTOR; 1.
DR Pfam; PF07715; Plug; 1.
DR Pfam; PF00593; TonB_dep_Rec; 1.
DR SUPFAM; SSF56935; Porins; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003357};
KW Reference proteome {ECO:0000313|Proteomes:UP000001522};
KW TonB box {ECO:0000256|ARBA:ARBA00023077, ECO:0000256|RuleBase:RU003357};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 63..159
FT /note="TonB-dependent receptor plug"
FT /evidence="ECO:0000259|Pfam:PF07715"
FT DOMAIN 294..684
FT /note="TonB-dependent receptor-like beta-barrel"
FT /evidence="ECO:0000259|Pfam:PF00593"
FT REGION 26..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 82841 MW; F342427D7B70FF4D CRC64;
MTKKNFYFLV FFLGLVCAQE AQETKKETKQ QTKKEAKNEE TPEEKQLNTI LASSEREFSF
TNKTMVSGQD FMERQVNNLT QMFEKESSIS VGGGGTRGQK VYIRGMEDRL LRVRIDGAAQ
NGNAFHHQGN LLIDATMIKN IELIKGAANA SVGPGALAGS MTVTTKSALD FLNPGQKVGF
RVETSAYTNY GVKESAAIYG SDRKYFDMLA LYNFLDIFYY RNGKHTFTNL FDPTPDDKVL
GSPSMQNNGL IKANVYFTSR DKFTFSYSII HDQAVRPLRS NVTRIDPNLN NGVDFALILF
RHRNMANNFS GVFEHKGTDR FSKPNIKFNA YGNLRNVRLT VFSINDPSVR QKDEEGTTPR
DLVLNNAGAD FEVKHALGNQ KKNALEYGIN YQNFATADRF VVPTATQRGR ENANIIGGYV
QANYYVLKNL SIGAGTRYDL YFYYDQNYQH HLTQGFSPSA VILWNPVESM DVKVSYSYVT
RGAIPADTLL LGDRTHFIAK NLKAEKGQNV ELDIDYHHEY FALRGAAFYQ NIKDFINSYG
IGHGYILADG ESFEYSIKDN LKYPVNIFGF EAGLDFFYEN FLASFSFSRS FPKVRGHLIN
DTYELGAAVG NTYVLKFAYD FKRVGLNISW LSRFVQRLKY TGYDIYNDEF SQVDKPGYMV
HNIYFTYIPP RHKNFTLYFA IENLFNAYYI SQSSPYKVSA DAKASESINA VRRALAEPGL
NAKLALVYKF
//
