ID D3UGC7_HELM1 Unreviewed; 275 AA.
AC D3UGC7;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Putative prephenate dehydrogenase {ECO:0000313|EMBL:CBG39548.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:CBG39548.1};
GN Name=tyrA {ECO:0000313|EMBL:CBG39548.1};
GN OrderedLocusNames=HMU02860 {ECO:0000313|EMBL:CBG39548.1};
OS Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198)
OS (Campylobacter mustelae).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=679897 {ECO:0000313|EMBL:CBG39548.1, ECO:0000313|Proteomes:UP000001522};
RN [1] {ECO:0000313|EMBL:CBG39548.1, ECO:0000313|Proteomes:UP000001522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43772 / LMG 18044 / NCTC 12198 / 12198
RC {ECO:0000313|Proteomes:UP000001522};
RX PubMed=20219135; DOI=10.1186/1471-2164-11-164;
RA O'Toole P.W., Snelling W.J., Canchaya C., Forde B.M., Hardie K.R.,
RA Josenhans C., Graham R.L.J., McMullan G., Parkhill J., Belda E.,
RA Bentley S.D.;
RT "Comparative genomics and proteomics of Helicobacter mustelae, an
RT ulcerogenic and carcinogenic gastric pathogen.";
RL BMC Genomics 11:164-164(2010).
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DR EMBL; FN555004; CBG39548.1; -; Genomic_DNA.
DR RefSeq; WP_013022641.1; NC_013949.1.
DR AlphaFoldDB; D3UGC7; -.
DR STRING; 679897.HMU02860; -.
DR KEGG; hms:HMU02860; -.
DR eggNOG; COG0287; Bacteria.
DR HOGENOM; CLU_055968_2_0_7; -.
DR Proteomes; UP000001522; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CBG39548.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001522}.
FT DOMAIN 1..275
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 275 AA; 30756 MW; 5DAC071BEEDF3B96 CRC64;
MQAGIIGLGL IGGSLGLALK ETKMFKMILG YDCNSLHMQQ ALSLGLIDEC IELHEIKQCD
VIFLAIPLDA ITKTLKNFGS LSPHSTIIDL GSAKEQILRE IPQNLRKNYI GAHPMCGTEN
NGPKAAIKGL FDKKIVILTS IEQSGEFQVA FCKEIFIAIG MQIVKMQAKE HDEHIALISH
LPHLISYALA NTVLEQEKKE FILTLIGGGF RDMSRISKSS PIMWRDIFKQ NRKNVLESLG
LFEKQIQAAQ QMLEKEDYQG LEKWMSNANS LKNFI
//
