ID D3UH88_HELM1 Unreviewed; 429 AA.
AC D3UH88;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Putative MCP-type signal transduction protein, PAS domain sensor protein {ECO:0000313|EMBL:CBG39860.1};
GN Name=tlpPAS {ECO:0000313|EMBL:CBG39860.1};
GN OrderedLocusNames=HMU05990 {ECO:0000313|EMBL:CBG39860.1};
OS Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198)
OS (Campylobacter mustelae).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=679897 {ECO:0000313|EMBL:CBG39860.1, ECO:0000313|Proteomes:UP000001522};
RN [1] {ECO:0000313|EMBL:CBG39860.1, ECO:0000313|Proteomes:UP000001522}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43772 / LMG 18044 / NCTC 12198 / 12198
RC {ECO:0000313|Proteomes:UP000001522};
RX PubMed=20219135; DOI=10.1186/1471-2164-11-164;
RA O'Toole P.W., Snelling W.J., Canchaya C., Forde B.M., Hardie K.R.,
RA Josenhans C., Graham R.L.J., McMullan G., Parkhill J., Belda E.,
RA Bentley S.D.;
RT "Comparative genomics and proteomics of Helicobacter mustelae, an
RT ulcerogenic and carcinogenic gastric pathogen.";
RL BMC Genomics 11:164-164(2010).
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; FN555004; CBG39860.1; -; Genomic_DNA.
DR RefSeq; WP_013022944.1; NC_013949.1.
DR AlphaFoldDB; D3UH88; -.
DR STRING; 679897.HMU05990; -.
DR KEGG; hms:HMU05990; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_26_7; -.
DR Proteomes; UP000001522; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00283; MA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001522};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284}.
FT DOMAIN 161..185
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 214..266
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 252..429
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 429 AA; 47627 MW; 37975645577F27C2 CRC64;
MFGNKEREDI SALKGRNFYL ENAIAAIREA TPGVILQPNG AIIDVTKDFV VMLNTSEEQI
RGRRFEDLMY PGFANSSEFL NVWNEAQSGK ISKFLMRCVG RGNRDLWLET ILLPIKGANN
QIERIIVLTN NITPLKEREL GLKGVVDAVQ RSMAGIEFKP DGTIIAANDN FLRTMGYSLD
EVVGKHHSMF CDPKFAKSQD YIKFWDNLRN GNFQSGMFER IAKNGKVIYL EASYNPIYDI
DGKVCKVIKF ASDVTAQVEK DKQKNDLALE LAQKNDQLTR DGKEVIEKTA QNVRSIAQTM
QTSSDLVASL NSQSDEIKSI IQTIKDIADQ TNLLALNAAI EAARAGEHGR GFAVVADEVR
KLAERTGKSI TEITTTINSI RDVTSQVVES INVSISEVED SVKLASEAKE FMDKIRASSE
EVAGAIAMQ
//
