ID D3UX06_XENBS Unreviewed; 217 AA.
AC D3UX06;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Cobalt-precorrin-8X methylmutase (Cobalt-precorrin isomerase) (HBA synthase) {ECO:0000313|EMBL:CBJ79991.1};
DE EC=5.4.1.2 {ECO:0000313|EMBL:CBJ79991.1};
GN OrderedLocusNames=XBJ1_0850 {ECO:0000313|EMBL:CBJ79991.1};
OS Xenorhabdus bovienii (strain SS-2004).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79991.1, ECO:0000313|Proteomes:UP000002045};
RN [1] {ECO:0000313|EMBL:CBJ79991.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79991.1};
RX PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C., de Leon L.,
RA Drace K., Du Z., Givaudan A., Herbert Tran E.E., Jewell K.A., Knack J.J.,
RA Krasomil-Osterfeld K.C., Kukor R., Lanois A., Latreille P.,
RA Leimgruber N.K., Lipke C.M., Liu R., Lu X., Martens E.C., Marri P.R.,
RA Medigue C., Menard M.L., Miller N.M., Morales-Soto N., Norton S.,
RA Ogier J.C., Orchard S.S., Park D., Park Y., Qurollo B.A., Sugar D.R.,
RA Richards G.R., Rouy Z., Slominski B., Slominski K., Snyder H., Tjaden B.C.,
RA van der Hoeven R., Welch R.D., Wheeler C., Xiang B., Barbazuk B.,
RA Gaudriault S., Goodner B., Slater S.C., Forst S., Goldman B.S.,
RA Goodrich-Blair H.;
RT "The entomopathogenic bacterial endosymbionts xenorhabdus and photorhabdus:
RT convergent lifestyles from divergent genomes.";
RL PLoS ONE 6:E27909-E27909(2011).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; FN667741; CBJ79991.1; -; Genomic_DNA.
DR RefSeq; WP_012987421.1; NC_013892.1.
DR AlphaFoldDB; D3UX06; -.
DR STRING; 406818.XBJ1_0850; -.
DR KEGG; xbo:XBJ1_0850; -.
DR PATRIC; fig|406818.4.peg.770; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_1_1_6; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000002045; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CBJ79991.1}.
FT DOMAIN 14..209
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 217 AA; 24209 MW; D16207A16D12BCEA CRC64;
MNYPQRSYIQ QPQQIEQHSF DIITGIIRES RPDYHFVDAG QEAVIKRVIH TTADFDWLDI
LHFSPDVLHR IRDGILRGCT LYTDTTMVLS GINKTRLAQY GSECRCYVSD PRVVQMAKVQ
QITRSMAAVD IALQESGEKI FVFGNAPTAL FRLLEHQSTP IAVVGVPVGF VGAEESKNAL
IHSDLSCIAA RGRKGGSNIA AAIINAVLYR MPEVRHE
//
