ID D3VDG7_XENNA Unreviewed; 354 AA.
AC D3VDG7;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Periplasmic serine endoprotease {ECO:0000313|EMBL:CBJ92207.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:CBJ92207.1};
GN Name=degS {ECO:0000313|EMBL:CBJ92207.1};
GN OrderedLocusNames=XNC1_4182 {ECO:0000313|EMBL:CBJ92207.1};
OS Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG
OS 1036 / NCIMB 9965 / AN6).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ92207.1, ECO:0000313|Proteomes:UP000008075};
RN [1] {ECO:0000313|EMBL:CBJ92207.1, ECO:0000313|Proteomes:UP000008075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 /
RC AN6 {ECO:0000313|Proteomes:UP000008075};
RX PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C., de Leon L.,
RA Drace K., Du Z., Givaudan A., Herbert Tran E.E., Jewell K.A., Knack J.J.,
RA Krasomil-Osterfeld K.C., Kukor R., Lanois A., Latreille P.,
RA Leimgruber N.K., Lipke C.M., Liu R., Lu X., Martens E.C., Marri P.R.,
RA Medigue C., Menard M.L., Miller N.M., Morales-Soto N., Norton S.,
RA Ogier J.C., Orchard S.S., Park D., Park Y., Qurollo B.A., Sugar D.R.,
RA Richards G.R., Rouy Z., Slominski B., Slominski K., Snyder H., Tjaden B.C.,
RA van der Hoeven R., Welch R.D., Wheeler C., Xiang B., Barbazuk B.,
RA Gaudriault S., Goodner B., Slater S.C., Forst S., Goldman B.S.,
RA Goodrich-Blair H.;
RT "The entomopathogenic bacterial endosymbionts xenorhabdus and photorhabdus:
RT convergent lifestyles from divergent genomes.";
RL PLoS ONE 6:E27909-E27909(2011).
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
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DR EMBL; FN667742; CBJ92207.1; -; Genomic_DNA.
DR RefSeq; WP_013185519.1; NC_014228.1.
DR AlphaFoldDB; D3VDG7; -.
DR STRING; 406817.XNC1_4182; -.
DR KEGG; xne:XNC1_4182; -.
DR eggNOG; COG0265; Bacteria.
DR HOGENOM; CLU_020120_2_2_6; -.
DR Proteomes; UP000008075; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011783; Pept_S1C_DegS.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02038; protease_degS; 1.
DR PANTHER; PTHR22939:SF101; PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CBJ92207.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000008075}.
FT DOMAIN 248..326
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 97
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611783-1"
FT ACT_SITE 127
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611783-1"
FT ACT_SITE 201
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611783-1"
FT BINDING 184
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR611783-2"
FT BINDING 259..264
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR611783-2"
SQ SEQUENCE 354 AA; 37715 MW; A8DC8EC136EAFF82 CRC64;
MLIKLLRSIV IGLLIAAILL VAIPSLRPNG FKNLLSGNNN YSDKVYSFSQ GVRRAAPAVV
NIYSSSMGSF SHESRELQPL GSGVIMSDKG YILTNKHVIN KAGSIIVALQ DGHFYEALLV
GSDGPTDLAV LKINATNLPV IPINPDRVPH VGDIVLAIGN PYNLGQTITQ GIISATGRVG
LSPTRRQYFL QTDASINQGN SGGALVNTLG ELVGINTLTF DKSEFGTTPE GLGFAIPTKL
ATTIMQKLIR DGRVIRGYIG ITARELPYIR SSGSNINQIQ GLRVFQVAPS GPAEKAGIKA
GDIIISVNRQ PAISPMETMD QVAEIRPGSL VPVTVLRDGK SLTLNVTIDD FDGY
//
