ID D3VL71_XENNA Unreviewed; 233 AA.
AC D3VL71;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Transcriptional repressor for multidrug efflux pump (TetR/AcrR family) {ECO:0000313|EMBL:CBJ89030.1};
GN Name=acrR {ECO:0000313|EMBL:CBJ89030.1};
GN OrderedLocusNames=XNC1_0959 {ECO:0000313|EMBL:CBJ89030.1};
OS Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG
OS 1036 / NCIMB 9965 / AN6).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ89030.1, ECO:0000313|Proteomes:UP000008075};
RN [1] {ECO:0000313|EMBL:CBJ89030.1, ECO:0000313|Proteomes:UP000008075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 /
RC AN6 {ECO:0000313|Proteomes:UP000008075};
RX PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C., de Leon L.,
RA Drace K., Du Z., Givaudan A., Herbert Tran E.E., Jewell K.A., Knack J.J.,
RA Krasomil-Osterfeld K.C., Kukor R., Lanois A., Latreille P.,
RA Leimgruber N.K., Lipke C.M., Liu R., Lu X., Martens E.C., Marri P.R.,
RA Medigue C., Menard M.L., Miller N.M., Morales-Soto N., Norton S.,
RA Ogier J.C., Orchard S.S., Park D., Park Y., Qurollo B.A., Sugar D.R.,
RA Richards G.R., Rouy Z., Slominski B., Slominski K., Snyder H., Tjaden B.C.,
RA van der Hoeven R., Welch R.D., Wheeler C., Xiang B., Barbazuk B.,
RA Gaudriault S., Goodner B., Slater S.C., Forst S., Goldman B.S.,
RA Goodrich-Blair H.;
RT "The entomopathogenic bacterial endosymbionts xenorhabdus and photorhabdus:
RT convergent lifestyles from divergent genomes.";
RL PLoS ONE 6:E27909-E27909(2011).
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DR EMBL; FN667742; CBJ89030.1; -; Genomic_DNA.
DR AlphaFoldDB; D3VL71; -.
DR STRING; 406817.XNC1_0959; -.
DR KEGG; xne:XNC1_0959; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_12_3_6; -.
DR Proteomes; UP000008075; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR013572; Tscrpt_reg_MAATS_C.
DR PANTHER; PTHR43479; ACREF/ENVCD OPERON REPRESSOR-RELATED; 1.
DR PANTHER; PTHR43479:SF11; ACREF_ENVCD OPERON REPRESSOR-RELATED; 1.
DR Pfam; PF08361; TetR_C_2; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000008075}.
FT DOMAIN 27..87
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 50..69
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 233 AA; 26831 MW; 5A20B868FBC601E8 CRC64;
MNVCKSASVK NKVYGIKMAR KTKQQAKQTR QQIIDAAIKT FSERGVSATS LSDIAIAAGV
TRGAIYWHFK NKTDLLSTVC KMPEDKIGAL EREYQAKYPN NPLLALRSLL IFMLRMMMHD
TEYRLLIEIF FHKCEFVGEI SSLEDELRET CISDYEKIEK WLACCIQSGE LPHNLELRRA
AIMLKALMTG LLENWSFSPD SFNVQEQSAY LVDGFIDTLK HSDYLRYSEE NEY
//
