ID D3YTK9_MOUSE Unreviewed; 452 AA.
AC D3YTK9;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Zinc finger and SCAN domain containing 2 {ECO:0000313|Ensembl:ENSMUSP00000121143.2};
DE Flags: Fragment;
GN Name=Zscan2 {ECO:0000313|Ensembl:ENSMUSP00000121143.2,
GN ECO:0000313|MGI:MGI:99176};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121143.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000121143.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121143.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000121143.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121143.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00187}.
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DR AlphaFoldDB; D3YTK9; -.
DR SMR; D3YTK9; -.
DR EPD; D3YTK9; -.
DR PeptideAtlas; D3YTK9; -.
DR ProteomicsDB; 359901; -.
DR Antibodypedia; 1841; 161 antibodies from 23 providers.
DR Ensembl; ENSMUST00000147125.2; ENSMUSP00000121143.2; ENSMUSG00000038797.14.
DR AGR; MGI:99176; -.
DR MGI; MGI:99176; Zscan2.
DR VEuPathDB; HostDB:ENSMUSG00000038797; -.
DR GeneTree; ENSGT00940000161710; -.
DR HOGENOM; CLU_002678_49_3_1; -.
DR OMA; ILLMHQR; -.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000038797; Expressed in spermatid and 72 other cell types or tissues.
DR ExpressionAtlas; D3YTK9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23235; KRUEPPEL-LIKE TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR23235:SF147; ZINC FINGER PROTEIN 2-LIKE-RELATED; 1.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 1: Evidence at protein level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW Proteomics identification {ECO:0007829|EPD:D3YTK9,
KW ECO:0007829|ProteomicsDB:D3YTK9};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 69..127
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT DOMAIN 222..249
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 250..277
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 278..305
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 306..333
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 334..361
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 362..389
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 390..417
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 418..445
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 42..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 452
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000121143.2"
SQ SEQUENCE 452 AA; 50314 MW; BAB827DE75A67C43 CRC64;
MAAEVPAVST PLSPLVQVPQ EEDEQAEVTT MILEDDAWVQ EAVLQEDGPE SEPFPQSAGK
GSPQEEDAAE GPQGALVRFR ELCRRWLRPE VHTKEQMLTV LPREIQAWLQ EHRPESSEEA
VALVEDLTQT FRHSDFEIQS ENGENSNEDM FEGVESHGMF LNISGGEGGQ QSDGDSDFER
DCGSGGAQGH APGEDPRVVP SEGREVGQLI GLQGTYLGEK PYECPQCGKT FSRKSHLITH
ERTHTGEKYY KCDECGKSFS DGSNFSRHQT THTGEKPYKC RDCGKSFSRS ANLITHQRIH
TGEKPFQCAE CGKSFSRSPN LIAHQRTHTG EKPYSCPECG KSFGNRSSLN THQGIHTGEK
PYACKECGES FSYNSNLIRH QRIHTGEKPY KCTECGQKFS QSSALITHRR THTGEKPYQC
GECGKNFSRS SNLATHRRTH LVEKPYKCGL CG
//
