ID D3YVF7_MOUSE Unreviewed; 144 AA.
AC D3YVF7;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Oxysterol binding protein-like 3 {ECO:0000313|Ensembl:ENSMUSP00000114472.2};
DE Flags: Fragment;
GN Name=Osbpl3 {ECO:0000313|Ensembl:ENSMUSP00000114472.2,
GN ECO:0000313|MGI:MGI:1918970};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000114472.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000114472.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114472.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000114472.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000114472.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; D3YVF7; -.
DR SMR; D3YVF7; -.
DR MaxQB; D3YVF7; -.
DR PeptideAtlas; D3YVF7; -.
DR ProteomicsDB; 326460; -.
DR Antibodypedia; 12224; 139 antibodies from 26 providers.
DR Ensembl; ENSMUST00000146341.4; ENSMUSP00000114472.2; ENSMUSG00000029822.16.
DR AGR; MGI:1918970; -.
DR MGI; MGI:1918970; Osbpl3.
DR VEuPathDB; HostDB:ENSMUSG00000029822; -.
DR GeneTree; ENSGT00940000155957; -.
DR HOGENOM; CLU_150392_0_0_1; -.
DR OMA; XAKYWST; -.
DR ChiTaRS; Osbpl3; mouse.
DR Proteomes; UP000000589; Chromosome 6.
DR Bgee; ENSMUSG00000029822; Expressed in urinary bladder urothelium and 179 other cell types or tissues.
DR ExpressionAtlas; D3YVF7; baseline and differential.
DR CDD; cd13287; PH_ORP3_ORP6_ORP7; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR14336:SF8; DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE; 1.
DR PANTHER; PTHR14336; TANDEM PH DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Proteomics identification {ECO:0007829|EPD:D3YVF7,
KW ECO:0007829|MaxQB:D3YVF7};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 50..144
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 144
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000114472.2"
SQ SEQUENCE 144 AA; 16679 MW; 26DDB1D1EE0DDDFD CRC64;
MSDEKNLGVS QKLVSPSRST SSCSSKQGSR QDSWEVVEGL RGEMTYTQEP PVQKGFLLKK
RKWPLKGWHK RFFCLEKGIL KYAKSQADIE REKLHGCIDV GLSVMSVKKS SKCIDLDTEE
HIYHLKVKSE ELFDEWVSKL RHHR
//
