ID D3Z0Q5_MOUSE Unreviewed; 242 AA.
AC D3Z0Q5;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=TGFB-induced factor homeobox 1 {ECO:0000313|Ensembl:ENSMUSP00000115375.2};
DE Flags: Fragment;
GN Name=Tgif1 {ECO:0000313|Ensembl:ENSMUSP00000115375.2,
GN ECO:0000313|MGI:MGI:1194497};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115375.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000115375.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115375.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000115375.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115375.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR AlphaFoldDB; D3Z0Q5; -.
DR SMR; D3Z0Q5; -.
DR MaxQB; D3Z0Q5; -.
DR ProteomicsDB; 373295; -.
DR Antibodypedia; 3890; 441 antibodies from 33 providers.
DR Ensembl; ENSMUST00000127719.2; ENSMUSP00000115375.2; ENSMUSG00000047407.18.
DR AGR; MGI:1194497; -.
DR MGI; MGI:1194497; Tgif1.
DR VEuPathDB; HostDB:ENSMUSG00000047407; -.
DR GeneTree; ENSGT00940000155230; -.
DR OMA; FPLCQSV; -.
DR ChiTaRS; Tgif1; mouse.
DR Proteomes; UP000000589; Chromosome 17.
DR Bgee; ENSMUSG00000047407; Expressed in embryonic post-anal tail and 224 other cell types or tissues.
DR ExpressionAtlas; D3Z0Q5; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR PANTHER; PTHR11850:SF59; HOMEOBOX PROTEIN TGIF1; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Proteomics identification {ECO:0007829|ProteomicsDB:D3Z0Q5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 13..76
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 15..77
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 242
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000115375.2"
SQ SEQUENCE 242 AA; 26435 MW; 54A6B208DF390945 CRC64;
MDSPLDLSSS AASGKRRRRG NLPKESVQIL RDWLYEHRYN AYPSEQEKAL LSQQTHLSTL
QVCNWFINAR RRLLPDMLRK DGKDPNQFTI SRRGAKISEA SSIEAAMGIK NFMPTLEESP
FHSCVVGPNP TLGRPVSPKP PSPGSILARP SVICHTTVTA LKDGPFSLCQ PIGVGQSTDV
PQIAPSNFTD TSLVYPEDTC KSGPSPNPQS GLFNTPPPTP PDLNQDFSGF QLLVDVALKR
AA
//
