ID D3Z117_MOUSE Unreviewed; 189 AA.
AC D3Z117;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=A disintegrin and metallopeptidase domain 12 (meltrin alpha) {ECO:0000313|Ensembl:ENSMUSP00000123161.2};
DE Flags: Fragment;
GN Name=Adam12 {ECO:0000313|Ensembl:ENSMUSP00000123161.2,
GN ECO:0000313|MGI:MGI:105378};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000123161.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000123161.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123161.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000123161.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123161.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3Z117; -.
DR ProteomicsDB; 346934; -.
DR Antibodypedia; 19223; 545 antibodies from 40 providers.
DR Ensembl; ENSMUST00000134504.8; ENSMUSP00000123161.2; ENSMUSG00000054555.12.
DR AGR; MGI:105378; -.
DR MGI; MGI:105378; Adam12.
DR VEuPathDB; HostDB:ENSMUSG00000054555; -.
DR GeneTree; ENSGT00940000155495; -.
DR HOGENOM; CLU_087486_0_0_1; -.
DR OMA; SYMLEPC; -.
DR ChiTaRS; Adam12; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000054555; Expressed in hindlimb mesenchyme and 209 other cell types or tissues.
DR ExpressionAtlas; D3Z117; baseline and differential.
DR InterPro; IPR002870; Peptidase_M12B_N.
DR PANTHER; PTHR11905; ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN; 1.
DR PANTHER; PTHR11905:SF112; DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF01562; Pep_M12B_propep; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Proteomics identification {ECO:0007829|PeptideAtlas:D3Z117,
KW ECO:0007829|ProteomicsDB:D3Z117};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 33..93
FT /note="Peptidase M12B propeptide"
FT /evidence="ECO:0000259|Pfam:PF01562"
FT NON_TER 189
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000123161.2"
SQ SEQUENCE 189 AA; 21038 MW; C0FE9AC8103E860D CRC64;
MSLWDQRGTY EVARASLLSK DPGIPGQSIP AKDHPDVLTV QLQLESRDLI LSLERNEGLI
ANGFTETHYL QDGTDVSLTR NHTDHCYYHG HVQGDAASVV SLSTCSGLRG LIMFENKTYS
LEPMKNTTDS YKLVPAESMT NIQGLCGSQH NKSNLTMEDV SPGTSQMRAR RHKRETLKMT
KYVELVIVA
//
