ID D3Z282_MOUSE Unreviewed; 225 AA.
AC D3Z282;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=TARBP2, RISC loading complex RNA binding subunit {ECO:0000313|Ensembl:ENSMUSP00000121748.2};
DE Flags: Fragment;
GN Name=Tarbp2 {ECO:0000313|Ensembl:ENSMUSP00000121748.2,
GN ECO:0000313|MGI:MGI:103027};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121748.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000121748.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121748.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000121748.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121748.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; D3Z282; -.
DR SMR; D3Z282; -.
DR MaxQB; D3Z282; -.
DR PeptideAtlas; D3Z282; -.
DR ProteomicsDB; 368126; -.
DR Antibodypedia; 15253; 461 antibodies from 35 providers.
DR Ensembl; ENSMUST00000146756.8; ENSMUSP00000121748.2; ENSMUSG00000023051.13.
DR AGR; MGI:103027; -.
DR MGI; MGI:103027; Tarbp2.
DR VEuPathDB; HostDB:ENSMUSG00000023051; -.
DR GeneTree; ENSGT00940000157748; -.
DR HOGENOM; CLU_048292_3_0_1; -.
DR OMA; QDKDAMG; -.
DR ChiTaRS; Tarbp2; mouse.
DR Proteomes; UP000000589; Chromosome 15.
DR Bgee; ENSMUSG00000023051; Expressed in spermatocyte and 70 other cell types or tissues.
DR ExpressionAtlas; D3Z282; baseline and differential.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19890; DSRM_TARBP2_rpt1; 1.
DR CDD; cd10844; DSRM_TARBP2_rpt2; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR044469; TRBP2_DSRM_1.
DR InterPro; IPR044470; TRBP2_DSRM_2.
DR PANTHER; PTHR46205; LOQUACIOUS, ISOFORM B; 1.
DR PANTHER; PTHR46205:SF1; RISC-LOADING COMPLEX SUBUNIT TARBP2; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:D3Z282,
KW ECO:0007829|MaxQB:D3Z282};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 9..76
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 137..205
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT NON_TER 225
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000121748.2"
SQ SEQUENCE 225 AA; 24196 MW; 196B58ACEB6EA5DB CRC64;
MLAANPGKTP ISLLQEYGTR IGKTPVYDLL KAEGQAHQPN FTFRVTVGDT SCTGQGPSKK
AAKHKAAEVA LKHLKGGSML EPALEDSSSF SLLDSSPPED TPVVAAEAAA PVPSAVLTRS
PPMEMQPPVS PQQSECNPVG ALQELVVQKG WRLPEYMVTQ ESGPAHRKEF TMTCRVERFI
EIGSGTSKKL AKRNAAAKML LRVHTVPLDA RDGNEAEPDD DHFSI
//
