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Database: UniProt
Entry: D4A8N6_RAT
LinkDB: D4A8N6_RAT
Original site: D4A8N6_RAT 
ID   D4A8N6_RAT              Unreviewed;       416 AA.
AC   D4A8N6;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 2.
DT   17-JUN-2020, entry version 64.
DE   SubName: Full=Tubulin epsilon and delta complex 1 {ECO:0000313|Ensembl:ENSRNOP00000030430};
GN   Name=Tedc1 {ECO:0000313|Ensembl:ENSRNOP00000030430,
GN   ECO:0000313|RGD:1596085};
GN   Synonyms=LOC690422 {ECO:0000313|RGD:1596085};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000030430, ECO:0000313|Proteomes:UP000002494};
RN   [1] {ECO:0000313|Ensembl:ENSRNOP00000030430, ECO:0000313|Proteomes:UP000002494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000030430,
RC   ECO:0000313|Proteomes:UP000002494};
RX   PubMed=15057822; DOI=10.1038/nature02426;
RG   Rat Genome Sequencing Project Consortium;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA   Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA   Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA   Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA   Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA   Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA   Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA   Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA   Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA   Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA   Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA   Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA   Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA   Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA   Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA   Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA   Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA   Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA   Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA   Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA   Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA   Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA   Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA   Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA   Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA   Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA   Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA   Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA   Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA   Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA   Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA   Mockrin S., Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into mammalian
RT   evolution.";
RL   Nature 428:493-521(2004).
RN   [2] {ECO:0000313|Ensembl:ENSRNOP00000030430}
RP   IDENTIFICATION.
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000030430};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AABR07065622; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; D4A8N6; -.
DR   STRING; 10116.ENSRNOP00000030430; -.
DR   PaxDb; D4A8N6; -.
DR   PRIDE; D4A8N6; -.
DR   Ensembl; ENSRNOT00000029223; ENSRNOP00000030430; ENSRNOG00000005153.
DR   UCSC; RGD:1596085; rat.
DR   RGD; 1596085; Tedc1.
DR   eggNOG; ENOG410IWUX; Eukaryota.
DR   eggNOG; ENOG4111XJF; LUCA.
DR   GeneTree; ENSGT00390000011474; -.
DR   HOGENOM; CLU_052124_0_0_1; -.
DR   OMA; SCTPGMG; -.
DR   OrthoDB; 1248596at2759; -.
DR   TreeFam; TF330945; -.
DR   Proteomes; UP000002494; Chromosome 6.
DR   Bgee; ENSRNOG00000005153; Expressed in testis and 8 other tissues.
DR   GO; GO:0005814; C:centriole; ISO:RGD.
DR   GO; GO:0005929; C:cilium; ISO:RGD.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISO:RGD.
DR   InterPro; IPR027996; DUF4509.
DR   InterPro; IPR028100; DUF4510.
DR   Pfam; PF14970; DUF4509; 1.
DR   Pfam; PF14971; DUF4510; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT   DOMAIN          42..216
FT                   /note="DUF4509"
FT                   /evidence="ECO:0000259|Pfam:PF14970"
FT   DOMAIN          254..414
FT                   /note="DUF4510"
FT                   /evidence="ECO:0000259|Pfam:PF14971"
SQ   SEQUENCE   416 AA;  46483 MW;  63D79D4328CD4F9D CRC64;
     MPLTIQDPLD LTRPQRSQQC SGLAYVHLWH GHCRNKPDRL LAPVLWQLLL RVLSPLAANN
     TWTDLAPEAQ ARVVKSALGS RGYPRSVLLQ FPDGSSQGSR ELLLALSWLL AQGPLLEQLL
     AQTRVQVGDQ LPQCEALTSP GPLACLVATK SPVDLRLVEW LMGKLRFRWR CLILSQREQC
     TLLSKIHLYT QGCHSQQSLG HLSVAETEML RDPESSQQLL HALESENARL EAALEWRRCE
     LVFWQWMDTV LDACSPETPA VTSQPTALPM ISEGGLGELE SVRQELLALQ EELREVAEPR
     RAAWESRVGG LGQGPEWSNS RKALREVVER ELADLQGSWK LCSTPAQPQR PHRLVRSKDG
     APRRQGLQAA EVIRTLSAKE DCLKKALHQL QCQCQQELAR LAGTLPGLIW VLPPGH
//
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