ID   D4AK83_ARTBC            Unreviewed;       757 AA.
AC   D4AK83;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Glycosyl hydrolase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ARB_04685 {ECO:0000313|EMBL:EFE37156.1};
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS   mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE37156.1, ECO:0000313|Proteomes:UP000008866};
RN   [1] {ECO:0000313|Proteomes:UP000008866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFE37156.1}.
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DR   EMBL; ABSU01000001; EFE37156.1; -; Genomic_DNA.
DR   RefSeq; XP_003017801.1; XM_003017755.1.
DR   AlphaFoldDB; D4AK83; -.
DR   STRING; 663331.D4AK83; -.
DR   GeneID; 9522648; -.
DR   KEGG; abe:ARB_04685; -.
DR   eggNOG; ENOG502QPU8; Eukaryota.
DR   HOGENOM; CLU_009024_0_1_1; -.
DR   OMA; GWKRDPQ; -.
DR   OrthoDB; 69117at2759; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR041036; GH5_C.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR31308; -; 1.
DR   PANTHER; PTHR31308:SF5; ERGOSTERYL-BETA-GLUCOSIDASE; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   Pfam; PF18564; Glyco_hydro_5_C; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          66..129
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
FT   DOMAIN          637..726
FT                   /note="Glycoside hydrolase family 5 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18564"
SQ   SEQUENCE   757 AA;  85813 MW;  BB59900A846C27F2 CRC64;
     MAPLRLRVEG NVFRDPHNRE VILRGINLDA TAKYPRIPDV PSHEVNGFFD ADDVSFVNRP
     FTLEDSHTHF SRLKKWGYNH IRYVFTWEAI EHTGPGQYDE EWITFTIELL RIAGSYGFYV
     YMDPHQDVWS RFSGGSGAPL WTLYAAGLDP RNFHDTQAAL VQNTYPDPAA FPKMIWSTNY
     TRLVCQTMFT LFWAGKDFAP KAIINGMNIQ DYLQTHFIAA CKHLAVRIHE TGELEDDVVI
     GWENVNEPHR GMIGIPDISV IPADQQLQLG TSPTAFQGMM TGSGFPCEVT QWEFGTFGPH
     QTGRTLVDPE GKSVWLKVDR ADQYGWKRDP QWKVGECIWA QHGVWDPATL TLLRSNYFGT
     HPRTGQALDY EGFINTYFLE HYRKYRDALR SVHKDTIMFC QPPVLEIPPT IKGTVDDDPN
     MVHAVHFYDG LTLMSKHWNR YYNVDVVGIL RGKYWIPAFG LKIGETAIRN SFRDQLHYLR
     EESYKNMGNH PLLLTETGIP YDMDDKYAYK TGDYSSQISA MDANHFGIEG CGGNGYSLWT
     YASENSHKWG DNWNGEDLSI YSPDDLELPI AKSLESGMTL LDPSSPSFSQ SRADSQAIRV
     EPSNLKAALP AASITPKPQL KESGEHRGFR AVEAFVRPGP EAVHGRITKH GFDLQNCTFT
     LSLTADSPTP SGAPTLIFLP ELHFPKDKST VTVSGGKWEI FSLEFQHGSI QFLKWWHAEG
     DQTIQIHGVK RELSAIVSPH DDEGYIEQCK QHSCIVM
//