ID D4AL83_ARTBC Unreviewed; 389 AA.
AC D4AL83;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=O-methyltransferase, putative {ECO:0000313|EMBL:EFE36142.1};
GN ORFNames=ARB_05080 {ECO:0000313|EMBL:EFE36142.1};
OS Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS mentagrophytes).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE36142.1, ECO:0000313|Proteomes:UP000008866};
RN [1] {ECO:0000313|Proteomes:UP000008866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE36142.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABSU01000002; EFE36142.1; -; Genomic_DNA.
DR RefSeq; XP_003016787.1; XM_003016741.1.
DR AlphaFoldDB; D4AL83; -.
DR GeneID; 9526264; -.
DR KEGG; abe:ARB_05080; -.
DR eggNOG; KOG3178; Eukaryota.
DR HOGENOM; CLU_005533_5_0_1; -.
DR OMA; WDPVDEG; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000008866; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EFE36142.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:EFE36142.1}.
FT DOMAIN 226..367
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 296
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 389 AA; 43023 MW; A4BB4E548E7345A6 CRC64;
MDSATALISK LQTLASRLSN EEDRDARKEC LQISKALTAQ LEEPENVAVD MIFSPMIAVS
ARIAVDLNLF ALIAKEEPVT SAKLAELSGA EELLIIRILR PLSAIHFVEE VAPKTWKATR
ITHAMAIEGI AAGHRMISRF VVISMQSAPA YLKKHGYACP TDPKDGLMQY AFNSKLSAFE
QVTSDPALLK DFNTFMGSTM GARRYWVDWY PVQDRIIDGA SPDKALLVDV GAGKGHDLLA
FQEKFPNAGR LVLEDLAAVT ETLDSLDPAI EKVPYDFYTE QPVIGARVYF YHHILHDWSD
ACCLKILEKV VAAMTPGYSK LLLHEMLVLD QAAPLFQAEL DMTMMAFNGG MERTKDQWTA
LLEKAGLKVV QFWDPVDEGG DGIVEAMKA
//
